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3D osteogenic differentiation of human iPSCs reveals the role of TGFß signal in the transition from progenitors to osteoblasts and osteoblasts to osteocytes.
Kawai, Shunsuke; Sunaga, Junko; Nagata, Sanae; Nishio, Megumi; Fukuda, Masayuki; Kamakura, Takeshi; Sun, Liping; Jin, Yonghui; Sakamoto, Satoko; Watanabe, Akira; Matsuda, Shuichi; Adachi, Taiji; Toguchida, Junya.
Afiliação
  • Kawai S; Department of Fundamental Cell Technology, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan. kawashun@cira.kyoto-u.ac.jp.
  • Sunaga J; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan. kawashun@cira.kyoto-u.ac.jp.
  • Nagata S; Department of Biosystems Science, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
  • Nishio M; Department of Fundamental Cell Technology, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.
  • Fukuda M; Department of Fundamental Cell Technology, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.
  • Kamakura T; Department of Regeneration Sciences and Engineering, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
  • Sun L; Department of Regeneration Sciences and Engineering, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
  • Jin Y; Department of Regeneration Sciences and Engineering, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
  • Sakamoto S; Department of Regeneration Sciences and Engineering, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
  • Watanabe A; Medical Innovation Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Matsuda S; Medical Innovation Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Adachi T; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Toguchida J; Department of Biosystems Science, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Sci Rep ; 13(1): 1094, 2023 01 19.
Article em En | MEDLINE | ID: mdl-36658197

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteócitos / Células-Tronco Pluripotentes Induzidas Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteócitos / Células-Tronco Pluripotentes Induzidas Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão