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Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmodium falciparum.
Kucharski, Michal; Wirjanata, Grennady; Nayak, Sourav; Boentoro, Josephine; Dziekan, Jerzy Michal; Assisi, Christina; van der Pluijm, Rob W; Miotto, Olivo; Mok, Sachel; Dondorp, Arjen M; Bozdech, Zbynek.
Afiliação
  • Kucharski M; School of Biological Sciences, Nanyang Technological University, Singapore.
  • Wirjanata G; School of Biological Sciences, Nanyang Technological University, Singapore.
  • Nayak S; School of Biological Sciences, Nanyang Technological University, Singapore.
  • Boentoro J; School of Biological Sciences, Nanyang Technological University, Singapore.
  • Dziekan JM; School of Biological Sciences, Nanyang Technological University, Singapore.
  • Assisi C; School of Biological Sciences, Nanyang Technological University, Singapore.
  • van der Pluijm RW; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
  • Miotto O; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Mok S; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Dondorp AM; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
  • Bozdech Z; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
PLoS Pathog ; 19(1): e1011118, 2023 01.
Article em En | MEDLINE | ID: mdl-36696458
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Resistência a Medicamentos / Malária Falciparum / Antimaláricos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Singapura
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Resistência a Medicamentos / Malária Falciparum / Antimaláricos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Singapura