Computing optimal drug dosing with OptiDose: implementation in NONMEM.

Bachmann, Freya; Koch, Gilbert; Bauer, Robert J; Steffens, Britta; Szinnai, Gabor; Pfister, Marc; Schropp, Johannes

Bachmann, Freya; Koch, Gilbert; Bauer, Robert J; Steffens, Britta; Szinnai, Gabor; Pfister, Marc; Schropp, Johannes.

Afiliação

Bachmann F; Department of Mathematics and Statistics, University of Konstanz, PO Box 195, 78457, Konstanz, Germany.
Koch G; Pediatric Pharmacology and Pharmacometrics, University of Basel Children's Hospital, Spitalstrasse 33, 4056, Basel, Switzerland. gilbert.koch@ukbb.ch.
Bauer RJ; ICON Clinical Research LLC, Blue Bell, PA, USA.
Steffens B; Pediatric Pharmacology and Pharmacometrics, University of Basel Children's Hospital, Spitalstrasse 33, 4056, Basel, Switzerland.
Szinnai G; Pediatric Endocrinology and Diabetology, University of Basel Children's Hospital, Spitalstrasse 33, 4056, Basel, Switzerland.
Pfister M; Department of Clinical Research, University of Basel and University Hospital Basel, Basel, Switzerland.
Schropp J; Pediatric Pharmacology and Pharmacometrics, University of Basel Children's Hospital, Spitalstrasse 33, 4056, Basel, Switzerland.

J Pharmacokinet Pharmacodyn ; 50(3): 173-188, 2023 06.

Article em En | MEDLINE | ID: mdl-36707456

Assuntos

Algoritmos; Software

Palavras-chave

Dose optimization; Optimal control; Optimal dosing; Pharmacometrics; Therapeutic goal

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Algoritmos / Software Tipo de estudo: Guideline Idioma: En Revista: J Pharmacokinet Pharmacodyn Assunto da revista: FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

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