Phosphoethanolamine cytidylyltransferase ameliorates mitochondrial function and apoptosis in hepatocytes in T2DM in vitro.

Xu, Hu; Li, Weizu; Huang, Lei; He, Xinyu; Xu, Bei; He, Xueqing; Chen, Wentong; Wang, Yaoxing; Xu, Wenjun; Wang, Sheng; Kong, Qin; Xu, Youzhi; Lu, Wenjie

Phosphoethanolamine cytidylyltransferase ameliorates mitochondrial function and apoptosis in hepatocytes in T2DM in vitro.

Xu, Hu; Li, Weizu; Huang, Lei; He, Xinyu; Xu, Bei; He, Xueqing; Chen, Wentong; Wang, Yaoxing; Xu, Wenjun; Wang, Sheng; Kong, Qin; Xu, Youzhi; Lu, Wenjie.

Afiliação

Xu H; Basic Medical College, Anhui Medical University, Hefei, China.
Li W; Basic Medical College, Anhui Medical University, Hefei, China.
Huang L; Basic Medical College, Anhui Medical University, Hefei, China.
He X; Basic Medical College, Anhui Medical University, Hefei, China.
Xu B; Basic Medical College, Anhui Medical University, Hefei, China.
He X; Basic Medical College, Anhui Medical University, Hefei, China.
Chen W; Basic Medical College, Anhui Medical University, Hefei, China.
Wang Y; Basic Medical College, Anhui Medical University, Hefei, China.
Xu W; Basic Medical College, Anhui Medical University, Hefei, China.
Wang S; Center for Scientific Research, Anhui Medical University, Hefei, China.
Kong Q; Basic Medical College, Anhui Medical University, Hefei, China.
Xu Y; Basic Medical College, Anhui Medical University, Hefei, China. Electronic address: xuyouzhi@ahmu.edu.cn.
Lu W; Basic Medical College, Anhui Medical University, Hefei, China. Electronic address: wenjie63136@163.com.

J Lipid Res ; 64(3): 100337, 2023 03.

Article em En | MEDLINE | ID: mdl-36716821

Assuntos

Diabetes Mellitus Tipo 2; Fosfatidiletanolaminas; Camundongos; Animais; Fosfatidiletanolaminas/metabolismo; Diabetes Mellitus Tipo 2/metabolismo; RNA Nucleotidiltransferases/metabolismo; Etanolaminas/farmacologia; Etanolaminas/metabolismo; Hepatócitos/metabolismo; Mitocôndrias/metabolismo; Apoptose; Trifosfato de Adenosina/metabolismo

Palavras-chave

ATP synthesis; cytidine-5'-diphosphate-ethanolamine pathway; high glucose and free fatty acids; lipidomics; liver; mitochondria; phosphatidylethanolamine; phosphatidylserine decarboxylase pathway; phospholipids; type 2 diabetes mellitus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatidiletanolaminas / Diabetes Mellitus Tipo 2 Limite: Animals Idioma: En Revista: J Lipid Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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