Impact of microbial genome completeness on metagenomic functional inference.
ISME Commun
; 3(1): 12, 2023 Feb 16.
Article
em En
| MEDLINE
| ID: mdl-36797336
ABSTRACT
Inferring the functional capabilities of bacteria from metagenome-assembled genomes (MAGs) is becoming a central process in microbiology. Here we show that the completeness of genomes has a significant impact on the recovered functional signal, spanning all domains of metabolic functions. We identify factors that affect this relationship between genome completeness and function fullness, and provide baseline knowledge to guide efforts to correct for this overlooked bias in metagenomic functional inference.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
ISME Commun
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Dinamarca