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Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor.
Darabedian, Narek; Ji, Wenzhi; Fan, Mengyang; Lin, Shan; Seo, Hyuk-Soo; Vinogradova, Ekaterina V; Yaron, Tomer M; Mills, Evanna L; Xiao, Haopeng; Senkane, Kristine; Huntsman, Emily M; Johnson, Jared L; Che, Jianwei; Cantley, Lewis C; Cravatt, Benjamin F; Dhe-Paganon, Sirano; Stegmaier, Kimberly; Zhang, Tinghu; Gray, Nathanael S; Chouchani, Edward T.
Afiliação
  • Darabedian N; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Ji W; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Fan M; Department of Chemical and Systems Biology, CHEM-H and SCI, Stanford Medical School, Stanford University, Stanford, CA, USA.
  • Lin S; Department of Chemical and Systems Biology, CHEM-H and SCI, Stanford Medical School, Stanford University, Stanford, CA, USA.
  • Seo HS; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Vinogradova EV; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Yaron TM; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Mills EL; Laboratory of Chemical Immunology and Proteomics, The Rockefeller University, New York, NY, USA.
  • Xiao H; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Senkane K; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
  • Huntsman EM; Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
  • Johnson JL; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Che J; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Cantley LC; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Cravatt BF; Department of Immunology, Harvard Medical School, Boston, MA, USA.
  • Dhe-Paganon S; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Stegmaier K; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Zhang T; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
  • Gray NS; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Chouchani ET; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
Nat Chem Biol ; 19(7): 815-824, 2023 07.
Article em En | MEDLINE | ID: mdl-36823351

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Creatina / Creatina Quinase Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Creatina / Creatina Quinase Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos