Relationship between blood-brain barrier changes and drug metabolism under high-altitude hypoxia: obstacle or opportunity for drug transport?

Liu, Guiqin; Bai, Xue; Yang, Jianxin; Duan, Yabin; Zhu, Junbo; Xiangyang, Li

Liu, Guiqin; Bai, Xue; Yang, Jianxin; Duan, Yabin; Zhu, Junbo; Xiangyang, Li.

Afiliação

Liu G; Research Center for High Altitude Medicine, Qinghai University Medical College, Xining, China.
Bai X; Research Center for High Altitude Medicine, Qinghai University Medical College, Xining, China.
Yang J; Research Center for High Altitude Medicine, Qinghai University Medical College, Xining, China.
Duan Y; Affiliated Hospital of Qinghai University, Xining, China.
Zhu J; Research Center for High Altitude Medicine, Qinghai University Medical College, Xining, China.
Xiangyang L; Research Center for High Altitude Medicine, Qinghai University Medical College, Xining, China.

Drug Metab Rev ; 55(1-2): 107-125, 2023.

Article em En | MEDLINE | ID: mdl-36823775

Assuntos

Doença da Altitude; Barreira Hematoencefálica; Humanos; Barreira Hematoencefálica/metabolismo; Doença da Altitude/metabolismo; Células Endoteliais/metabolismo; Hipóxia/metabolismo; Transporte Biológico

Palavras-chave

Bloodbrain barrier; drug transport; drug transporters; drug-metabolizing enzymes; high-altitude hypoxia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Doença da Altitude Limite: Humans Idioma: En Revista: Drug Metab Rev Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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