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Application of a genetic signature of late GU toxicity in SCIMITAR, a Post-op SBRT trial.
Kishan, Amar U; Marco, Nicholas; Ma, Ting Martin; Steinberg, Michael L; Sachdeva, Ankush; Cao, Minsong; Ballas, Leslie K; Rietdorf, Emily; Telesca, Donatello; Weidhaas, Joanne B.
Afiliação
  • Kishan AU; University of California, Department of Radiation Oncology, Los Angeles, CA 90025, USA.
  • Marco N; University of California, Department of Statistics, Los Angeles, CA 90025, USA.
  • Ma TM; University of California, Department of Radiation Oncology, Los Angeles, CA 90025, USA.
  • Steinberg ML; University of California, Department of Radiation Oncology, Los Angeles, CA 90025, USA.
  • Sachdeva A; University of California, Institute of Urologic Oncology, Los Angeles, CA 90025, USA.
  • Cao M; University of California, Department of Radiation Oncology, Los Angeles, CA 90025, USA.
  • Ballas LK; Cedars Sinai, Department of Radiation Oncology, Los Angeles, CA 90048, USA.
  • Rietdorf E; University of California, Department of Radiation Oncology, Los Angeles, CA 90025, USA.
  • Telesca D; University of California, Department of Statistics, Los Angeles, CA 90025, USA.
  • Weidhaas JB; University of California, Department of Radiation Oncology, Los Angeles, CA 90025, USA.
Clin Transl Radiat Oncol ; 39: 100594, 2023 Mar.
Article em En | MEDLINE | ID: mdl-36880064
Predictors of genitourinary toxicity after post-prostatectomy radiotherapy remain elusive. A previously defined germline DNA signature (PROSTOX) has shown predictive ability for late grade ≥ 2 GU toxicity after intact prostate stereotactic body radiotherapy. We explore whether PROSTOX would predict toxicity among patients receiving post-prostatectomy SBRT on a phase II clinical trial.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Clin Transl Radiat Oncol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Clin Transl Radiat Oncol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos