The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for ß-Cell Function In Vivo.

Davidson, Rebecca K; Kanojia, Sukrati; Wu, Wenting; Kono, Tatsuyoshi; Xu, Jerry; Osmulski, Meredith; Bone, Robert N; Casey, Nolan; Evans-Molina, Carmella; Sims, Emily K; Spaeth, Jason M

The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for ß-Cell Function In Vivo.

Davidson, Rebecca K; Kanojia, Sukrati; Wu, Wenting; Kono, Tatsuyoshi; Xu, Jerry; Osmulski, Meredith; Bone, Robert N; Casey, Nolan; Evans-Molina, Carmella; Sims, Emily K; Spaeth, Jason M.

Afiliação

Davidson RK; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN.
Kanojia S; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Wu W; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Kono T; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN.
Xu J; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Osmulski M; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Bone RN; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Casey N; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN.
Evans-Molina C; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN.
Sims EK; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Spaeth JM; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.

Diabetes ; 72(6): 746-757, 2023 06 01.

Article em En | MEDLINE | ID: mdl-36913741

Assuntos

Cromatina; Diabetes Mellitus Tipo 2; Camundongos; Animais; Humanos; Cromatina/genética; Complexo Mi-2 de Remodelação de Nucleossomo e Desacetilase/genética; Diabetes Mellitus Tipo 2/genética; DNA Helicases/genética; Camundongos Knockout; Expressão Gênica; Glucose

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Diabetes Mellitus Tipo 2 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Diabetes Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia

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