Investigate the immunogenic and protective effect of trivalent chimeric protein containing IpaD-StxB-TolC antigens as a vaccine candidate against S. dysenteri and S. flexneri.

Fathi, Javad; Amani, Jafar; Nazarian, Shahram; Hadi, Nahal; Mirhosseini, Seyed Ali; Ranjbar, Reza; Abianeh, Hossein Samiei

Fathi, Javad; Amani, Jafar; Nazarian, Shahram; Hadi, Nahal; Mirhosseini, Seyed Ali; Ranjbar, Reza; Abianeh, Hossein Samiei.

Afiliação

Fathi J; Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: javadfathi70@yahoo.com.
Amani J; Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: jafar.amani@gmail.com.
Nazarian S; Department of Biological Sciences, Faculty of Science, Imam Hossein University, Tehran, Iran. Electronic address: kpnazari@ihu.ac.ir.
Hadi N; Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Mirhosseini SA; Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Ranjbar R; Molecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Abianeh HS; Department of Medical Biotechnology and Nanotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Microb Pathog ; 178: 106066, 2023 May.

Article em En | MEDLINE | ID: mdl-36924900

Assuntos

Disenteria Bacilar; Escherichia coli; Animais; Camundongos; Escherichia coli/genética; Antígenos de Bactérias/genética; Vacinas Bacterianas; Disenteria Bacilar/prevenção & controle; Proteínas Recombinantes/genética; Toxinas Shiga; Proteínas Recombinantes de Fusão/genética; Anticorpos Antibacterianos; Shigella flexneri/genética; Camundongos Endogâmicos BALB C

Palavras-chave

IpaD; Recombinant protein; Shigella spp; StxB and TolC; Vaccine candidate

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Disenteria Bacilar / Escherichia coli Limite: Animals Idioma: En Revista: Microb Pathog Assunto da revista: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Ano de publicação: 2023 Tipo de documento: Article

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