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Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.
Patel, Parasvi S; Algouneh, Arash; Krishnan, Rehna; Reynolds, John J; Nixon, Kevin C J; Hao, Jun; Lee, Jihoon; Feng, Yue; Fozil, Chehronai; Stanic, Mia; Yerlici, Talya; Su, Peiran; Soares, Fraser; Liedtke, Elisabeth; Prive, Gil; Baider, Gary D; Pujana, Miquel Angel; Mekhail, Karim; He, Housheng Hansen; Hakem, Anne; Stewart, Grant S; Hakem, Razqallah.
Afiliação
  • Patel PS; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.
  • Algouneh A; Department of Medical Biophysics, University of Toronto, OntarioM5G 1L7, Canada.
  • Krishnan R; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.
  • Reynolds JJ; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, OntarioM5S 1A8, Canada.
  • Nixon KCJ; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.
  • Hao J; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
  • Lee J; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.
  • Feng Y; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.
  • Fozil C; Department of Cell and Systems Biology, University of Toronto, OntarioM5S 3G5, Canada.
  • Stanic M; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.
  • Yerlici T; Department of Medical Biophysics, University of Toronto, OntarioM5G 1L7, Canada.
  • Su P; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.
  • Soares F; Department of Medical Biophysics, University of Toronto, OntarioM5G 1L7, Canada.
  • Liedtke E; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, OntarioM5S 1A8, Canada.
  • Prive G; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.
  • Baider GD; Department of Medical Biophysics, University of Toronto, OntarioM5G 1L7, Canada.
  • Pujana MA; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.
  • Mekhail K; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.
  • He HH; Department of Medical Biophysics, University of Toronto, OntarioM5G 1L7, Canada.
  • Hakem A; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.
  • Stewart GS; Terrence Donnelly Centre for Cellular and Biomedical Research, University of Toronto, Toronto, ON, Canada.
  • Hakem R; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Barcelona 08908, Catalonia, Spain.
Nucleic Acids Res ; 51(9): 4341-4362, 2023 05 22.
Article em En | MEDLINE | ID: mdl-36928661
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Proteína BRCA1 / Replicação do DNA / Síndrome Hereditária de Câncer de Mama e Ovário / Mutação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Proteína BRCA1 / Replicação do DNA / Síndrome Hereditária de Câncer de Mama e Ovário / Mutação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá