IntestLine: a shiny-based application to map the rolled intestinal tissue onto a line.
Bioinformatics
; 39(4)2023 04 03.
Article
em En
| MEDLINE
| ID: mdl-36943334
ABSTRACT
SUMMARY:
To allow the comprehensive histological analysis of the whole intestine, it is often rolled to a spiral before imaging. This Swiss-rolling technique facilitates robust experimental procedures, but it limits the possibilities to comprehend changes along the intestine. Here, we present IntestLine, a Shiny-based open-source application for processing imaging data of (rolled) intestinal tissues and subsequent mapping onto a line. The visualization of the mapped data facilitates the assessment of the whole intestine in both proximal-distal and serosa-luminal axis, and enables the observation of location-specific cell types and markers. Accordingly, IntestLine can serve as a tool to characterize the intestine in multi-modal imaging studies. AVAILABILITY AND IMPLEMENTATION Source code can be found at Zenodo (https//doi.org/10.5281/zenodo.7081864) and GitHub (https//github.com/SchlitzerLab/IntestLine).
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Processamento de Imagem Assistida por Computador
/
Software
/
Intestinos
Idioma:
En
Revista:
Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Alemanha