Exposure to nanoplastics induces mitochondrial impairment and cytomembrane destruction in Leydig cells.

Sun, Zhangbei; Wen, Yiqian; Zhang, Fan; Fu, Zhendong; Yuan, Yangyang; Kuang, Haibin; Kuang, Xiaodong; Huang, Jian; Zheng, Liping; Zhang, Dalei

Sun, Zhangbei; Wen, Yiqian; Zhang, Fan; Fu, Zhendong; Yuan, Yangyang; Kuang, Haibin; Kuang, Xiaodong; Huang, Jian; Zheng, Liping; Zhang, Dalei.

Afiliação

Sun Z; School of Basic Medical Sciences, Nanchang University, Nanchang 330006, PR China.
Wen Y; School of Basic Medical Sciences, Nanchang University, Nanchang 330006, PR China.
Zhang F; School of Basic Medical Sciences, Nanchang University, Nanchang 330006, PR China.
Fu Z; School of Basic Medical Sciences, Nanchang University, Nanchang 330006, PR China.
Yuan Y; Clinical Medical Experimental Center of Nanchang University, Nanchang 330031, PR China.
Kuang H; School of Basic Medical Sciences, Nanchang University, Nanchang 330006, PR China.
Kuang X; School of Basic Medical Sciences, Nanchang University, Nanchang 330006, PR China.
Huang J; Clinical Medical Experimental Center of Nanchang University, Nanchang 330031, PR China.
Zheng L; Clinical Medical Experimental Center of Nanchang University, Nanchang 330031, PR China; Jiangxi Provincial Key Laboratory of Reproductive Physiology and Pathology, Nanchang 330006, PR China. Electronic address: zhengliping@ncu.edu.cn.
Zhang D; School of Basic Medical Sciences, Nanchang University, Nanchang 330006, PR China; Jiangxi Provincial Key Laboratory of Reproductive Physiology and Pathology, Nanchang 330006, PR China. Electronic address: zhangdalei@ncu.edu.cn.

Ecotoxicol Environ Saf ; 255: 114796, 2023 Apr 15.

Article em En | MEDLINE | ID: mdl-36948006

Assuntos

Células Intersticiais do Testículo; Nanopartículas; Camundongos; Animais; Masculino; Humanos; Células Intersticiais do Testículo/metabolismo; Microplásticos/metabolismo; Poliestirenos/toxicidade; Plásticos/metabolismo; Nanopartículas/toxicidade; Nanopartículas/metabolismo; Testosterona/metabolismo

Palavras-chave

Apoptosis; Mitochondrial dysfunction; Oxidative stress; PS-NPs; Reproductive toxicity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas / Células Intersticiais do Testículo Limite: Animals / Humans / Male Idioma: En Revista: Ecotoxicol Environ Saf Ano de publicação: 2023 Tipo de documento: Article

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