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Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.
Fritschi, Christopher J; Anang, Saumya; Gong, Zhen; Mohammadi, Mohammadjavad; Richard, Jonathan; Bourassa, Catherine; Severino, Kenny T; Richter, Hannah; Yang, Derek; Chen, Hung-Ching; Chiu, Ta-Jung; Seaman, Michael S; Madani, Navid; Abrams, Cameron; Finzi, Andrés; Hendrickson, Wayne A; Sodroski, Joseph G; Smith, Amos B.
Afiliação
  • Fritschi CJ; Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104.
  • Anang S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Gong Z; Department of Microbiology, Harvard Medical School, Boston, MA 02115.
  • Mohammadi M; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032.
  • Richard J; Department of Chemical and Biological Engineering, Drexel University, Philadelphia, PA 19104.
  • Bourassa C; Centre de Recherche du CHUM, Montreal, QC H2X 0A9, Canada.
  • Severino KT; Departement de Microbiologie, Infectiologie et Immunologie, Universite de Montreal, Montreal, QC H3T 1J4, Canada.
  • Richter H; Departement de Microbiologie, Infectiologie et Immunologie, Universite de Montreal, Montreal, QC H3T 1J4, Canada.
  • Yang D; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA 02215.
  • Chen HC; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA 02215.
  • Chiu TJ; Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104.
  • Seaman MS; Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104.
  • Madani N; Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104.
  • Abrams C; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA 02215.
  • Finzi A; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Hendrickson WA; Department of Microbiology, Harvard Medical School, Boston, MA 02115.
  • Sodroski JG; Department of Chemical and Biological Engineering, Drexel University, Philadelphia, PA 19104.
  • Smith AB; Centre de Recherche du CHUM, Montreal, QC H2X 0A9, Canada.
Proc Natl Acad Sci U S A ; 120(13): e2222073120, 2023 03 28.
Article em En | MEDLINE | ID: mdl-36961924
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / Soropositividade para HIV Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / Soropositividade para HIV Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2023 Tipo de documento: Article