Analysis of genetic dominance in the UK Biobank.

Palmer, Duncan S; Zhou, Wei; Abbott, Liam; Wigdor, Emilie M; Baya, Nikolas; Churchhouse, Claire; Seed, Cotton; Poterba, Tim; King, Daniel; Kanai, Masahiro; Bloemendal, Alex; Neale, Benjamin M

Palmer, Duncan S; Zhou, Wei; Abbott, Liam; Wigdor, Emilie M; Baya, Nikolas; Churchhouse, Claire; Seed, Cotton; Poterba, Tim; King, Daniel; Kanai, Masahiro; Bloemendal, Alex; Neale, Benjamin M.

Afiliação

Palmer DS; Analytical and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Zhou W; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Abbott L; Analytical and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Wigdor EM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Baya N; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Churchhouse C; Analytical and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Seed C; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Poterba T; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
King D; Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Kanai M; Analytical and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Bloemendal A; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Neale BM; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Science ; 379(6639): 1341-1348, 2023 03 31.

Article em En | MEDLINE | ID: mdl-36996212

Assuntos

Bancos de Espécimes Biológicos; Genes Dominantes; Variação Genética; Herança Multifatorial; Animais; Humanos; Cruzamento; Genótipo; Modelos Genéticos; Fenótipo; Polimorfismo de Nucleotídeo Único; Reino Unido

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Variação Genética / Bancos de Espécimes Biológicos / Herança Multifatorial / Genes Dominantes Tipo de estudo: Prognostic_studies Limite: Animals / Humans País/Região como assunto: Europa Idioma: En Revista: Science Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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