Natural killer cell-mimic nanoparticles can actively target and kill acute myeloid leukemia cells.

Alizadeh Zeinabad, Hojjat; Yeoh, Wen Jie; Arif, Maryam; Lomora, Mihai; Banz, Yara; Riether, Carsten; Krebs, Philippe; Szegezdi, Eva

Alizadeh Zeinabad, Hojjat; Yeoh, Wen Jie; Arif, Maryam; Lomora, Mihai; Banz, Yara; Riether, Carsten; Krebs, Philippe; Szegezdi, Eva.

Afiliação

Alizadeh Zeinabad H; Apoptosis Research Centre, School of Biological and Chemical Sciences, University of Galway, Galway, Ireland; Cell Stress Discoveries, University of Galway Business Innovation Centre, Galway, Ireland.
Yeoh WJ; Institute of Pathology, University of Bern, Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Switzerland.
Arif M; Apoptosis Research Centre, School of Biological and Chemical Sciences, University of Galway, Galway, Ireland.
Lomora M; School of Biological and Chemical Sciences, University of Galway, Galway, Ireland; CÚRAM, Science Foundation Ireland Research Centre for Medical Devices, University of Galway, Galway, Ireland.
Banz Y; Institute of Pathology, University of Bern, Bern, Switzerland.
Riether C; Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Krebs P; Institute of Pathology, University of Bern, Bern, Switzerland.
Szegezdi E; Apoptosis Research Centre, School of Biological and Chemical Sciences, University of Galway, Galway, Ireland; CÚRAM, Science Foundation Ireland Research Centre for Medical Devices, University of Galway, Galway, Ireland. Electronic address: eva.szegezdi@universityofgalway.ie.

Biomaterials ; 298: 122126, 2023 07.

Article em En | MEDLINE | ID: mdl-37094524

Assuntos

Leucemia Mieloide Aguda; Nanopartículas; Humanos; Ligantes; Células Matadoras Naturais; Leucemia Mieloide Aguda/tratamento farmacológico; Apoptose; Fator de Necrose Tumoral alfa; Citotoxicidade Imunológica

Palavras-chave

AML; Fc-binding receptor (CD16); Liposome nanoparticle; Natural killer (NK) cell; Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL); Tumor targeting

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Nanopartículas Limite: Humans Idioma: En Revista: Biomaterials Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Irlanda

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