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Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse.
Conway, James R W; Warren, Sean C; Lee, Young-Kyung; McCulloch, Andrew T; Magenau, Astrid; Lee, Victoria; Metcalf, Xanthe L; Stoehr, Janett; Haigh, Katharina; Abdulkhalek, Lea; Guaman, Cristian S; Reed, Daniel A; Murphy, Kendelle J; Pereira, Brooke A; Mélénec, Pauline; Chambers, Cecilia; Latham, Sharissa L; Lenthall, Helen; Deenick, Elissa K; Ma, Yuanqing; Phan, Tri; Lim, Elgene; Joshua, Anthony M; Walters, Stacey; Grey, Shane T; Shi, Yan-Chuan; Zhang, Lei; Herzog, Herbert; Croucher, David R; Philp, Andy; Scheele, Colinda L G J; Herrmann, David; Sansom, Owen J; Morton, Jennifer P; Papa, Antonella; Haigh, Jody J; Nobis, Max; Timpson, Paul.
Afiliação
  • Conway JRW; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Warren SC; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.
  • Lee YK; Turku Bioscience Centre, University of Turku and Åbo Akademi University, FI-20520 Turku, Finland.
  • McCulloch AT; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Magenau A; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Lee V; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.
  • Metcalf XL; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Stoehr J; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Haigh K; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Abdulkhalek L; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Guaman CS; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Reed DA; School of Clinical Medicine, UNSW Sydney, Randwick Clinical Campus, Sydney, NSW, Australia.
  • Murphy KJ; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Pereira BA; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.
  • Mélénec P; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Chambers C; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Latham SL; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Lenthall H; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Deenick EK; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Ma Y; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Phan T; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Lim E; Department of Pharmacology and Therapeutics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
  • Joshua AM; CancerCare Manitoba Research Institute, Winnipeg, Manitoba, Canada.
  • Walters S; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Grey ST; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Shi YC; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Zhang L; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Herzog H; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Croucher DR; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Philp A; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Scheele CLGJ; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.
  • Herrmann D; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Sansom OJ; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Morton JP; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW 2010, Australia.
  • Papa A; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Haigh JJ; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
  • Nobis M; Cancer Ecosystems Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Timpson P; Garvan Institute of Medical Research & The Kinghorn Cancer Centre, Sydney, NSW 2010, Australia.
Sci Adv ; 9(17): eadf9063, 2023 04 28.
Article em En | MEDLINE | ID: mdl-37126544
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Proteínas Proto-Oncogênicas c-akt Limite: Animals Idioma: En Revista: Sci Adv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Proteínas Proto-Oncogênicas c-akt Limite: Animals Idioma: En Revista: Sci Adv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Austrália