A novel system for rapid conversion of Gardner embryo grades to linear scale numeric variables.
Reprod Biomed Online
; 46(5): 808-818, 2023 05.
Article
em En
| MEDLINE
| ID: mdl-37130622
ABSTRACT
RESEARCH QUESTION Can Gardner embryo grades be converted to numeric interval variables to improve the incorporation of embryo grading in statistical analyses? DESIGN:
An equation that can be used to convert Gardner embryo grades to regular interval scale variables was developed the numerical embryo quality scoring index (NEQsi). The NEQsi system was then validated with a retrospective chart analysis assessing IVF cycles (nâ¯=â¯1711) conducted at a single Canadian fertility centre between 2014 and 2022. Gardner embryo grades on file were assigned using EmbryoScope and converted to NEQsi scores. Descriptive statistics, univariate logistic regressions and generalized estimating equations with cycle outcomes were prepared to demonstrate the relationship between NEQsi score and probability of pregnancy.RESULTS:
NEQsi produces interval numerical scores that range from 2 to 11. Patient case files in which single embryo transfers occurred (nâ¯=â¯1711) were examined and the Gardner embryo grades on file were converted to NEQsi scores. NEQsi scores ranged from 3 to 11, with a median score of 9. A positive linear relationship existed between the NEQsi scores and the probability of pregnancy (as assessed by quantitative ß-HCG). The NEQsi score was a significant predictor of pregnancy (P < 0.001).CONCLUSION:
Gardner embryo grades can be converted to interval variables and used directly statistical analyses.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fertilização in vitro
/
Fertilidade
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Pregnancy
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Reprod Biomed Online
Assunto da revista:
MEDICINA REPRODUTIVA
Ano de publicação:
2023
Tipo de documento:
Article