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A DddA ortholog-based and transactivator-assisted nuclear and mitochondrial cytosine base editors with expanded target compatibility.
Guo, Junfan; Yu, Wenxia; Li, Min; Chen, Hongyu; Liu, Jie; Xue, Xiaowen; Lin, Jianxiang; Huang, Shisheng; Shu, Wenjie; Huang, Xingxu; Liu, Zhen; Wang, Shengqi; Qiao, Yunbo.
Afiliação
  • Guo J; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
  • Yu W; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200125, China; WLA Laboratories, Shanghai 201208, China.
  • Li M; Shanghai Institute of Precision Medicine, Shanghai 200125, China; Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
  • Chen H; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, CAS Key Laboratory of Primate Neurobiology, State Key Laboratory of Neuroscience, Chinese Academy of Sciences, Shanghai 200031, China.
  • Liu J; Guangzhou Medical University, Guangzhou 511436, China.
  • Xue X; Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
  • Lin J; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200125, China; Shanghai Institute of Precision Medicine, Shanghai 200125, China.
  • Huang S; Zhejiang Lab, Hangzhou 311121, Zhejiang, China.
  • Shu W; Bioinformatics Center of AMMS, Beijing 100850, China.
  • Huang X; Zhejiang Lab, Hangzhou 311121, Zhejiang, China; Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou 310029, China.
  • Liu Z; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, CAS Key Laboratory of Primate Neurobiology, State Key Laboratory of Neuroscience, Chinese Academy of Sciences, Shanghai 200031, China. Electronic address: zliu2010@ion.ac.cn.
  • Wang S; Bioinformatics Center of AMMS, Beijing 100850, China. Electronic address: sqwang@bmi.ac.cn.
  • Qiao Y; Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200125, China; Shanghai Institute of Precision Medicine, Shanghai 200125, China. Electronic address: ybqiao@shsmu.edu.cn.
Mol Cell ; 83(10): 1710-1724.e7, 2023 05 18.
Article em En | MEDLINE | ID: mdl-37141888
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transativadores / Edição de Genes Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transativadores / Edição de Genes Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China