Submerged cultivation of Nigrospora sp. in batch and fed-batch modes for microbial oil production.
Nat Prod Res
; 38(10): 1662-1669, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-37211779
ABSTRACT
Microbial lipids are a valuable source of potential biofuels and essential polyunsaturated fatty acids. The optimization of the fermentation conditions is a strategy that affects the total lipid concentration. The genus Nigrospora sp. has been the target of investigations based on its potential bioherbicidal action. Therefore, this study developed a strategy to maximize the biomass concentration and lipid accumulation by Nigrospora sp. in submerged fermentation. Different media compositions and process variables were investigated in shaken flasks and bioreactor in batch and fed-batch modes. Maximum biomass concentration and lipid accumulations were 40.17 g/L and 21.32 wt% in the bioreactor, which was 2.1 and 5.4 times higher than the same condition in shaken flasks, respectively. This study presents relevant information to the production of fungal lipids since few investigations are exploring the fed-batch strategy to increase the yield of fungi lipids, as well as few studies investigating Nigrospora sp. to produce lipids.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ascomicetos
/
Reatores Biológicos
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Brasil