Atrial fibrillation increases the risk of new-onset myocardial infarction amongst working-age population: a propensity-matched study.
Herz
; 48(5): 408-412, 2023 Oct.
Article
em En
| MEDLINE
| ID: mdl-37264124
ABSTRACT
OBJECTIVE:
The aim of this study was to investigate the association between atrial fibrillation (AF) and new-onset myocardial infarction (MI) among a working-age population in an industrial city of North China.METHODS:
In total 77,670 participants aged under 60 years were selected for this cohort study. Participants were divided into an AF group (nâ¯= 121) and a non-AF group (nâ¯= 74,565) based on their medical histories. Thereafter, 121 participants from the AF group were propensity-matched with 363 participants from the non-AF group. All participants were followed up from June 2006 to December 2020; new-onset MI was regarded as the endpoint of this study. Multivariate Cox proportional hazards regression analysis models were designed to analyze the correlation between AF and new-onset MI.RESULTS:
During the 14-year follow-up, eight cases of new-onset MI were documented in the AF group, while five cases were documented in the non-AF group. The cumulative incidence of new-onset MI in the AF group (7.40%) was markedly higher than in the non-AF group (1.41%; pâ¯< 0.001). Atrial fibrillation was associated with an increased risk of new-onset MI in both univariate analysis (hazard ratio 5.202, 95% confidence interval [CI] 1.700-15.913) and multivariable-adjusted analysis (hazard ratio 5.335, 95% CI 1.683-16.910).CONCLUSION:
Atrial fibrillation increased the risk of new-onset MI amongst working-age individuals in an industrial city of North China.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fibrilação Atrial
/
Infarto do Miocárdio
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Herz
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China