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A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance.
Grimes, Samantha L; Choi, Young J; Banerjee, Anoosha; Small, Gabriel; Anderson-Daniels, Jordan; Gribble, Jennifer; Pruijssers, Andrea J; Agostini, Maria L; Abu-Shmais, Alexandra; Lu, Xiaotao; Darst, Seth A; Campbell, Elizabeth; Denison, Mark R.
Afiliação
  • Grimes SL; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center , Nashville, Tennessee, USA.
  • Choi YJ; Laboratory of Molecular Biophysics, The Rockefeller University , New York, New York, USA.
  • Banerjee A; Laboratory of Molecular Biophysics, The Rockefeller University , New York, New York, USA.
  • Small G; Tri-Institutional Program in Chemical Biology, The Rockefeller University , New York, New York, USA.
  • Anderson-Daniels J; Laboratory of Molecular Biophysics, The Rockefeller University , New York, New York, USA.
  • Gribble J; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center , Nashville, Tennessee, USA.
  • Pruijssers AJ; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center , Nashville, Tennessee, USA.
  • Agostini ML; Department of Pediatrics, Vanderbilt University Medical Center , Nashville, Tennessee, USA.
  • Abu-Shmais A; Vanderbilt Institute for Infection, Immunology and Inflammation , Nashville, Tennessee, USA.
  • Lu X; Department of Pediatrics, Vanderbilt University Medical Center , Nashville, Tennessee, USA.
  • Darst SA; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center , Nashville, Tennessee, USA.
  • Campbell E; Department of Pediatrics, Vanderbilt University Medical Center , Nashville, Tennessee, USA.
  • Denison MR; Laboratory of Molecular Biophysics, The Rockefeller University , New York, New York, USA.
mBio ; 14(4): e0106023, 2023 08 31.
Article em En | MEDLINE | ID: mdl-37338298
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Hepatite Murina / COVID-19 Limite: Animals / Humans Idioma: En Revista: MBio Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Hepatite Murina / COVID-19 Limite: Animals / Humans Idioma: En Revista: MBio Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos