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MAGT1 Deficiency Dysregulates Platelet Cation Homeostasis and Accelerates Arterial Thrombosis and Ischemic Stroke in Mice.
Gotru, Sanjeev Kiran; Mammadova-Bach, Elmina; Sogkas, Georgios; Schuhmann, Michael K; Schmitt, Karen; Kraft, Peter; Herterich, Sabine; Mamtimin, Medina; Pinarci, Akif; Beck, Sarah; Stritt, Simon; Han, Chao; Ren, Pengxuan; Freund, Jean-Noël; Klemann, Christian; Ringshausen, Felix C; Heemskerk, Johan W M; Dietrich, Alexander; Nieswandt, Bernhard; Stoll, Guido; Gudermann, Thomas; Braun, Attila.
Afiliação
  • Gotru SK; Institute of Experimental Biomedicine, University Hospital and Rudolf Virchow Center (S.K.G., K.S., S.B., S.S., B.N., A.B.), University of Würzburg, Germany.
  • Mammadova-Bach E; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians University, Munich, Germany (E.M.-B., M.M., A.P., C.H., A.D., T.G., A.B.).
  • Sogkas G; Division of Nephrology, Department of Medicine IV, Ludwig-Maximilians University Hospital, Munich, Germany (E.M.-B., M.M., C.H.).
  • Schuhmann MK; Cluster of Excellence RESIST (G. Sogkas), Hannover Medical School (MHH), Germany.
  • Schmitt K; Rheumatology and Immunology (G. Sogkas), Hannover Medical School (MHH), Germany.
  • Kraft P; Department of Neurology, University Hospital of Würzburg, Germany (M.K.S., P.K., G. Stoll).
  • Herterich S; Institute of Experimental Biomedicine, University Hospital and Rudolf Virchow Center (S.K.G., K.S., S.B., S.S., B.N., A.B.), University of Würzburg, Germany.
  • Mamtimin M; Department of Neurology, University Hospital of Würzburg, Germany (M.K.S., P.K., G. Stoll).
  • Pinarci A; Department of Neurology, Hospital Main-Spessart, Lohr, Germany (P.K.).
  • Beck S; Institute for Clinical Biochemistry and Pathobiochemistry (S.H.), University of Würzburg, Germany.
  • Stritt S; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians University, Munich, Germany (E.M.-B., M.M., A.P., C.H., A.D., T.G., A.B.).
  • Han C; Division of Nephrology, Department of Medicine IV, Ludwig-Maximilians University Hospital, Munich, Germany (E.M.-B., M.M., C.H.).
  • Ren P; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians University, Munich, Germany (E.M.-B., M.M., A.P., C.H., A.D., T.G., A.B.).
  • Freund JN; Institute of Experimental Biomedicine, University Hospital and Rudolf Virchow Center (S.K.G., K.S., S.B., S.S., B.N., A.B.), University of Würzburg, Germany.
  • Klemann C; Institute of Experimental Biomedicine, University Hospital and Rudolf Virchow Center (S.K.G., K.S., S.B., S.S., B.N., A.B.), University of Würzburg, Germany.
  • Ringshausen FC; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians University, Munich, Germany (E.M.-B., M.M., A.P., C.H., A.D., T.G., A.B.).
  • Heemskerk JWM; Division of Nephrology, Department of Medicine IV, Ludwig-Maximilians University Hospital, Munich, Germany (E.M.-B., M.M., C.H.).
  • Dietrich A; School of Life Science and Technology, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, China (P.R.).
  • Nieswandt B; INSERM, IRFAC/UMR-S1113, FMTS, University of Strasbourg, France (J.-N.F.).
  • Stoll G; Department of Women and Child Health, Center of Pediatric Research (CPL), Hospital for Children and Adolescents, Leipzig University, Germany (C.K.).
  • Gudermann T; Department of Respiratory Medicine (F.C.R.), Hannover Medical School (MHH), Germany.
  • Braun A; Biomedical Research in Obstructive and End-Stage Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Germany (F.C.R.).
Arterioscler Thromb Vasc Biol ; 43(8): 1494-1509, 2023 08.
Article em En | MEDLINE | ID: mdl-37381987
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombose / Infarto da Artéria Cerebral Média / Proteínas de Transporte de Cátions / AVC Isquêmico / Homeostase Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Arterioscler Thromb Vasc Biol Assunto da revista: ANGIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombose / Infarto da Artéria Cerebral Média / Proteínas de Transporte de Cátions / AVC Isquêmico / Homeostase Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Arterioscler Thromb Vasc Biol Assunto da revista: ANGIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha