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Clinical standards for drug-susceptible TB in children and adolescents.
Chiang, S S; Graham, S M; Schaaf, H S; Marais, B J; Sant'Anna, C C; Sharma, S; Starke, J R; Triasih, R; Achar, J; Amanullah, F; Armitage, L Y; Aurilio, R B; Buck, W C; Centis, R; Chabala, C; Cruz, A T; Demers, A-M; du Preez, K; Enimil, A; Furin, J; Garcia-Prats, A J; Gonzalez, N E; Hoddinott, G; Isaakidis, P; Jaganath, D; Kabra, S K; Kampmann, B; Kay, A; Kitai, I; Lopez-Varela, E; Maleche-Obimbo, E; Malaspina, F Mestanza; Velásquez, J Niederbacher; Nuttall, J J C; Oliwa, J N; Andrade, I Orozco; Perez-Velez, C M; Rabie, H; Seddon, J A; Sekadde, M P; Shen, A; Skrahina, A; Soriano-Arandes, A; Steenhoff, A P; Tebruegge, M; Tovar, M A; Tsogt, B; van der Zalm, M M; Welch, H; Migliori, G B.
Afiliação
  • Chiang SS; Division of Pediatric Infectious Diseases, Department of Pediatrics, Alpert Medical School of Brown University, Providence, RI, Center for International Health Research, Rhode Island Hospital, Providence, RI, USA.
  • Graham SM; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Burnet Institute, Melbourne, VIC, Australia.
  • Schaaf HS; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Marais BJ; Department of Paediatrics and Child Health and the Sydney Infectious Diseases Institute (Sydney ID), Sydney, NSW, Department of Infectious Diseases, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • Sant'Anna CC; Department of Paediatrics, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
  • Sharma S; Department of Paediatrics, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
  • Starke JR; Department of Pediatrics, Baylor College of Medicine, Houston, TX, Section of Infectious Diseases, Texas Children's Hospital, Houston, TX, USA.
  • Triasih R; Department of Paediatrics, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr Sardjito Hospital, Yogyakarta, Indonesia.
  • Achar J; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
  • Amanullah F; Department of Paediatrics, The Indus Hospital and Health Network, Karachi, Department of Paediatrics, The Aga Khan University Hospital, Karachi, Pakistan.
  • Armitage LY; Heartland National TB Center, University of Texas Health Science Center at Tyler, San Antonio, TX, USA.
  • Aurilio RB; Department of Paediatrics, Instituto de Puericultura e Pediatria Martagão Gesteira, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Department of Paediatrics, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
  • Buck WC; Department of Pediatrics, University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA, USA.
  • Centis R; Respiratory Diseases Clinical Epidemiology Unit, Istituti Clinici Scientifici Maugeri, Istituto di Ricovero e Cura a Carattere Scientifico, Tradate, Italy.
  • Chabala C; School of Medicine, Department of Paediatrics and Child Health, University of Zambia, Lusaka, Children's Hospital, University Teaching Hospitals, Lusaka, Zambia.
  • Cruz AT; Department of Pediatrics, Baylor College of Medicine, Houston, TX.
  • Demers AM; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa, Division of Microbiology, Department of Laboratory Medicine, CHU Sainte-Justine, Montreal, Canada.
  • du Preez K; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Enimil A; Department of Child Health, Kwame Nkrumah University of Science and Technology, Kumasi, Department of Child Health, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
  • Furin J; Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, Division of Infectious Diseases, Department of Medicine, Case Western Reserve University, Cleveland, OH.
  • Garcia-Prats AJ; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa, Department of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA.
  • Gonzalez NE; División Neumotisiología, Hospital de Niños Pedro de Elizalde, Buenos Aires, Dirección General de Posgrado, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
  • Hoddinott G; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Isaakidis P; Southern Africa Medical Unit (SAMU), Médecins Sans Frontières, Cape Town, South Africa, Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece.
  • Jaganath D; Division of Pediatric Infectious Diseases, Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA.
  • Kabra SK; Department of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
  • Kampmann B; Charite Centre for Global Health, Charite Universitatsmedizin Berlin, Berlin, Germany, Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.
  • Kay A; Department of Pediatrics, Baylor College of Medicine, Houston, TX.
  • Kitai I; Department of Paediatrics, Hospital for Sick Children, Toronto, ON, Department of Pediatrics, University of Toronto, Toronto, ON, Canada.
  • Lopez-Varela E; Hospital Clínic and ISGlobal, Universitat de Barcelona, Barcelona, Spain, Centro de Investigação em Saúde de Manhiça (CISM), Manhiça, Mozambique.
  • Maleche-Obimbo E; Department of Paediatrics & Child Health, University of Nairobi, Nairobi, Kenya.
  • Malaspina FM; Department of Paediatrics, Hospital San Bartólome, Lima, Red Peruana de Tuberculosis Pediátrica, Dirección de Prevención y Control de Tuberculosis, Ministerio de Salud, Lima, Perú.
  • Velásquez JN; Department of Paediatrics, Universidad Industrial de Santander, Bucaramanga, Board of Directors, Asociación Colombiana de Neumología Pediátrica, Bogotá, Colombia.
  • Nuttall JJC; Paediatric Infectious Diseases Unit, Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.
  • Oliwa JN; Faculty of Health Sciences, Department of Paediatrics and Child Health, The University of Nairobi, Nairobi, Health Services Unit, Kenya Medical Research Institute-Wellcome Trust Research Programme, Nairobi, Kenya.
  • Andrade IO; Center of Diagnosis and Integral Treatment for Tuberculosis, Servicios Médicos de la Frontera, Juárez, Medical Coordination, Juntos Binational Tuberculosis Project, Juárez, México.
  • Perez-Velez CM; Division of Infectious Diseases, Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.
  • Rabie H; Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Seddon JA; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa, Department of Infectious Disease, Imperial College London, London, UK.
  • Sekadde MP; National TB and Leprosy Program, Ministry of Health, Kampala, Uganda.
  • Shen A; Beijing Paediatric Research Institute, National Centre for Children's Health, Beijing Children's Hospital, Capital Medical University, Beijing, Pediatric Research Institute, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
  • Skrahina A; Clinical Department, The Republican Scientific and Practical Centre for Pulmonology and TB, Minsk, Belarus.
  • Soriano-Arandes A; Paediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Barcelona, Infection and Immunity in Children, Vall d'Hebron Research Institute, Barcelona, Spain.
  • Steenhoff AP; Global Health Center and Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA, Department of Paediatric & Adolescent Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
  • Tebruegge M; Department of Infection, Immunity & Inflammation, University College London, Great Ormond Street Institute of Child Health, London, UK, Department of Paediatrics, Klinik Ottakring, Wiener Gesundheitsverbund, Vienna, Austria.
  • Tovar MA; Socios En Salud Sucursal Perú, Escuela de Medicina, Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Perú.
  • Tsogt B; Research and Innovation, Mongolian Anti-TB Coalition, Ulaanbaatar, Mongolia.
  • van der Zalm MM; Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Welch H; Department of Pediatrics, Baylor College of Medicine, Houston, TX, Department of Paediatrics, The University of Papua New Guinea School of Medicine and Health Sciences, Port Moresby, Papua New Guinea.
  • Migliori GB; Respiratory Diseases Clinical Epidemiology Unit, Istituti Clinici Scientifici Maugeri, Istituto di Ricovero e Cura a Carattere Scientifico, Tradate, Italy.
Int J Tuberc Lung Dis ; 27(8): 584-598, 2023 08 01.
Article em En | MEDLINE | ID: mdl-37491754
ABSTRACT

BACKGROUND:

These clinical standards aim to provide guidance for diagnosis, treatment, and management of drug-susceptible TB in children and adolescents.

METHODS:

Fifty-two global experts in paediatric TB participated in a Delphi consensus process. After eight rounds of revisions, 51/52 (98%) participants endorsed the final document.

RESULTS:

Eight standards were identified Standard 1, Age and developmental stage are critical considerations in the assessment and management of TB; Standard 2, Children and adolescents with symptoms and signs of TB disease should undergo prompt evaluation, and diagnosis and treatment initiation should not depend on microbiological confirmation; Standard 3, Treatment initiation is particularly urgent in children and adolescents with presumptive TB meningitis and disseminated (miliary) TB; Standard 4, Children and adolescents should be treated with an appropriate weight-based regimen; Standard 5, Treating TB infection (TBI) is important to prevent disease; Standard 6, Children and adolescents should receive home-based/community-based treatment support whenever possible; Standard 7, Children, adolescents, and their families should be provided age-appropriate support to optimise engagement in care and clinical outcomes; and Standard 8, Case reporting and contact tracing should be conducted for each child and adolescent.

CONCLUSION:

These consensus-based clinical standards, which should be adapted to local contexts, will improve the care of children and adolescents affected by TB.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose Meníngea Tipo de estudo: Guideline / Prognostic_studies Limite: Adolescent / Child / Humans Idioma: En Revista: Int J Tuberc Lung Dis Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose Meníngea Tipo de estudo: Guideline / Prognostic_studies Limite: Adolescent / Child / Humans Idioma: En Revista: Int J Tuberc Lung Dis Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos