Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - Part IV: the ECETOC and CLE Proposal for a Thyroid Function-Related Neurodevelopmental Toxicity Testing and Assessment Scheme (Thyroid-NDT-TAS).

Melching-Kollmuss, Stephanie; Bothe, Kathrin; Charlton, Alex; Gangadharan, Babunilayam; Ghaffari, Rashin; Jacobi, Sylvia; Marty, Sue; Marxfeld, Heike-Antje; McInnes, Elizabeth F; Sauer, Ursula G; Sheets, Larry P; Strupp, Christian; Tinwell, Helen; Wiemann, Christiane; Botham, Philip A; van Ravenzwaay, Bennard

Melching-Kollmuss, Stephanie; Bothe, Kathrin; Charlton, Alex; Gangadharan, Babunilayam; Ghaffari, Rashin; Jacobi, Sylvia; Marty, Sue; Marxfeld, Heike-Antje; McInnes, Elizabeth F; Sauer, Ursula G; Sheets, Larry P; Strupp, Christian; Tinwell, Helen; Wiemann, Christiane; Botham, Philip A; van Ravenzwaay, Bennard.

Afiliação

Melching-Kollmuss S; BASF SE, Limburgerhof, Germany.
Bothe K; Bayer AG, CropScience, Monheim, Germany.
Charlton A; Syngenta Crop Protection, Greensboro, NC, USA.
Gangadharan B; Bayer SAS, Lyon, France.
Ghaffari R; Corteva Agriscience, Newark, DE, USA.
Jacobi S; SJ-Consult, Wiesbaden, Germany.
Marty S; Dow, Inc, Midland, MI, USA.
Marxfeld HA; BASF SE, Ludwigshafen, Germany.
McInnes EF; Syngenta, Jealott's Hill, Bracknell, United Kingdom.
Sauer UG; Scientific Consultancy - Animal Welfare, Neubiberg, Germany.
Sheets LP; Bayer CropScience, Chesterfield, MO, USA.
Strupp C; Gowan Crop Protection Ltd, Reading, United Kingdom.
Tinwell H; Bayer SAS, Lyon, France.
Wiemann C; BASF Oesterreich GmbH, Vienna, Austria.
Botham PA; Syngenta, Jealott's Hill, Bracknell, United Kingdom.
van Ravenzwaay B; Environmental Sciences Consulting, Altrip, Germany.

Crit Rev Toxicol ; 53(6): 339-371, 2023 07.

Article em En | MEDLINE | ID: mdl-37554099

Assuntos

Disruptores Endócrinos; Glândula Tireoide; Animais; Humanos; Disruptores Endócrinos/toxicidade; Testes de Toxicidade; Ecotoxicologia; Hormônios Tireóideos; Medição de Risco

Palavras-chave

Endocrine disruptor; adverse outcome pathway (AOP); cognitive function (learning and memory); deiodinase (DIO); developmental neurotoxicity study (DNT study; OECD TG 426); extended one-generation reproductive toxicity study (EOGRTS; OECD TG 443); liver enzyme induction; mode-of-action (MoA); motor activity; sodium-iodide symporter (NIS); thyroid modality; thyroid peroxidase (TPO); uridine diphosphate glucuronyltransferase (UGT); weight-of-evidence (WoE)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glândula Tireoide / Disruptores Endócrinos Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Crit Rev Toxicol Assunto da revista: TOXICOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

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