On the development of physiologically based toxicokinetic (PBTK) models for cardiovascular implants.

Giakoumi, Matheos; Stephanou, Pavlos S; Kapnisis, Konstantinos; Anayiotos, Andreas

Giakoumi, Matheos; Stephanou, Pavlos S; Kapnisis, Konstantinos; Anayiotos, Andreas.

Afiliação

Giakoumi M; Department of Mechanical Engineering and Materials Science and Engineering, Cyprus University of Technology, Limassol, 3036, Cyprus. Electronic address: matheos.giakoumis97@hotmail.com.
Stephanou PS; Department of Chemical Engineering, Cyprus University of Technology, Limassol, 3036, Cyprus. Electronic address: pavlos.stefanou@cut.ac.cy.
Kapnisis K; Department of Mechanical Engineering and Materials Science and Engineering, Cyprus University of Technology, Limassol, 3036, Cyprus. Electronic address: k.kapnisis@cut.ac.cy.
Anayiotos A; Department of Mechanical Engineering and Materials Science and Engineering, Cyprus University of Technology, Limassol, 3036, Cyprus. Electronic address: andreas.anayiotos@cut.ac.cy.

Regul Toxicol Pharmacol ; 144: 105489, 2023 Oct.

Article em En | MEDLINE | ID: mdl-37659713

Assuntos

Pulmão; Modelos Biológicos; Humanos; Animais; Suínos; Distribuição Tecidual; Toxicocinética; Porco Miniatura; Medição de Risco

Palavras-chave

Monte Carlo uncertainty estimation; Multi-objective optimization; Nickel leaching; Physiologically based toxicokinetic (PBTK) models; Stents; Toxicological risk assessment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pulmão / Modelos Biológicos Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Regul Toxicol Pharmacol Ano de publicação: 2023 Tipo de documento: Article

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