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Kupffer cell-like syncytia replenish resident macrophage function in the fibrotic liver.
Peiseler, Moritz; Araujo David, Bruna; Zindel, Joel; Surewaard, Bas G J; Lee, Woo-Yong; Heymann, Felix; Nusse, Ysbrand; Castanheira, Fernanda V S; Shim, Raymond; Guillot, Adrien; Bruneau, Alix; Atif, Jawairia; Perciani, Catia; Ohland, Christina; Ganguli Mukherjee, Priyanka; Niehrs, Annika; Thuenauer, Roland; Altfeld, Marcus; Amrein, Mathias; Liu, Zhaoyuan; Gordon, Paul M K; McCoy, Kathy; Deniset, Justin; MacParland, Sonya; Ginhoux, Florent; Tacke, Frank; Kubes, Paul.
Afiliação
  • Peiseler M; Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
  • Araujo David B; Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Zindel J; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum and Campus Charité Mitte, Berlin, Germany.
  • Surewaard BGJ; Berlin Institute of Health (BIH), Berlin, Germany.
  • Lee WY; Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
  • Heymann F; Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Nusse Y; Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
  • Castanheira FVS; Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Shim R; Department of Visceral Surgery and Medicine, Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland.
  • Guillot A; Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
  • Bruneau A; Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Atif J; Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
  • Perciani C; Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Ohland C; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum and Campus Charité Mitte, Berlin, Germany.
  • Ganguli Mukherjee P; Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
  • Niehrs A; Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Thuenauer R; Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
  • Altfeld M; Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Amrein M; Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
  • Liu Z; Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Gordon PMK; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum and Campus Charité Mitte, Berlin, Germany.
  • McCoy K; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow Klinikum and Campus Charité Mitte, Berlin, Germany.
  • Deniset J; Ajmera Transplant Centre, Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada.
  • MacParland S; Ajmera Transplant Centre, Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada.
  • Ginhoux F; Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
  • Tacke F; Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Kubes P; Department of Cell Biology and Anatomy, University of Calgary, Calgary, Alberta, Canada.
Science ; 381(6662): eabq5202, 2023 09 08.
Article em En | MEDLINE | ID: mdl-37676943
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Gigantes / Infecções Transmitidas por Sangue / Células de Kupffer / Cirrose Hepática Limite: Animals / Humans Idioma: En Revista: Science Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Gigantes / Infecções Transmitidas por Sangue / Células de Kupffer / Cirrose Hepática Limite: Animals / Humans Idioma: En Revista: Science Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá