Nrf2 depletion in the context of loss-of-function Keap1 leads to mitolysosome accumulation.

Dayalan Naidu, Sharadha; Angelova, Plamena R; Knatko, Elena V; Leonardi, Chiara; Novak, Miroslav; de la Vega, Laureano; Ganley, Ian G; Abramov, Andrey Y; Dinkova-Kostova, Albena T

Dayalan Naidu, Sharadha; Angelova, Plamena R; Knatko, Elena V; Leonardi, Chiara; Novak, Miroslav; de la Vega, Laureano; Ganley, Ian G; Abramov, Andrey Y; Dinkova-Kostova, Albena T.

Afiliação

Dayalan Naidu S; Jacqui Wood Cancer Centre, Division of Cellular and Systems Medicine, School of Medicine, University of Dundee, Dundee, UK.
Angelova PR; UCL Queen Square Institute of Neurology, Queen Square, London, UK.
Knatko EV; Jacqui Wood Cancer Centre, Division of Cellular and Systems Medicine, School of Medicine, University of Dundee, Dundee, UK.
Leonardi C; Jacqui Wood Cancer Centre, Division of Cellular and Systems Medicine, School of Medicine, University of Dundee, Dundee, UK.
Novak M; Jacqui Wood Cancer Centre, Division of Cellular and Systems Medicine, School of Medicine, University of Dundee, Dundee, UK.
de la Vega L; Jacqui Wood Cancer Centre, Division of Cellular and Systems Medicine, School of Medicine, University of Dundee, Dundee, UK.
Ganley IG; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK.
Abramov AY; UCL Queen Square Institute of Neurology, Queen Square, London, UK. Electronic address: a.abramov@ucl.ac.uk.
Dinkova-Kostova AT; Jacqui Wood Cancer Centre, Division of Cellular and Systems Medicine, School of Medicine, University of Dundee, Dundee, UK; Department of Pharmacology and Molecular Sciences and Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: a.dinkovakost

Free Radic Biol Med ; 208: 478-493, 2023 11 01.

Article em En | MEDLINE | ID: mdl-37714439

Assuntos

Neoplasias Pulmonares; Fator 2 Relacionado a NF-E2; Humanos; Proteínas Culina/genética; Proteínas Culina/metabolismo; Peptídeos e Proteínas de Sinalização Intracelular/genética; Peptídeos e Proteínas de Sinalização Intracelular/metabolismo; Proteína 1 Associada a ECH Semelhante a Kelch/genética; Proteína 1 Associada a ECH Semelhante a Kelch/metabolismo; Neoplasias Pulmonares/genética; Fator 2 Relacionado a NF-E2/genética; Fator 2 Relacionado a NF-E2/metabolismo; Mitocôndrias/metabolismo; Células A549

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator 2 Relacionado a NF-E2 / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Free Radic Biol Med Assunto da revista: BIOQUIMICA / MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido

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