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The lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism.
Oh, Mihee; Jang, Seo Young; Lee, Ji-Yoon; Kim, Jong Woo; Jung, Youngae; Kim, Jiwoo; Seo, Jinho; Han, Tae-Su; Jang, Eunji; Son, Hye Young; Kim, Dain; Kim, Min Wook; Park, Jin-Sung; Song, Kwon-Ho; Oh, Kyoung-Jin; Kim, Won Kon; Bae, Kwang-Hee; Huh, Yong-Min; Kim, Soon Ha; Kim, Doyoun; Han, Baek-Soo; Lee, Sang Chul; Hwang, Geum-Sook; Lee, Eun-Woo.
Afiliação
  • Oh M; Biodefense Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Korea.
  • Jang SY; Integrated Metabolomics Research Group, Western Seoul Center, Korea Basic Science Institute, Seoul, 03759, Korea.
  • Lee JY; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Korea.
  • Kim JW; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Korea.
  • Jung Y; Department of Functional Genomics, University of Science and Technology (UST), Daejeon, 34141, Korea.
  • Kim J; Integrated Metabolomics Research Group, Western Seoul Center, Korea Basic Science Institute, Seoul, 03759, Korea.
  • Seo J; Therapeutics and Biotechnology Department, Drug Discovery Platform Research Center, Korea Research Institute of Chemical Technology (KRICT), Daejeon, 34114, Korea.
  • Han TS; Graduate School of New Drug Discovery and Development, Chungnam National University, Daejeon, 305-764, Korea.
  • Jang E; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Korea.
  • Son HY; Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Korea.
  • Kim D; MediBio-Informatics Research Center, Novomics Co., Ltd., Seoul, Korea.
  • Kim MW; YUHS-KRIBB Medical Convergence Research Institute, Seoul, 03722, Korea.
  • Park JS; Department of Radiology, College of Medicine, Yonsei University, Seoul, 03722, Korea.
  • Song KH; Integrated Metabolomics Research Group, Western Seoul Center, Korea Basic Science Institute, Seoul, 03759, Korea.
  • Oh KJ; Department of Life Science, Ewha Womans University, Seoul, 03760, Korea.
  • Kim WK; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Korea.
  • Bae KH; MitoImmune Therapeutics Inc., Seoul, 06123, Korea.
  • Huh YM; Department of Cell Biology, Daegu Catholic University School of Medicine, Daegu, 42472, Korea.
  • Kim SH; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Korea.
  • Kim D; Department of Functional Genomics, University of Science and Technology (UST), Daejeon, 34141, Korea.
  • Han BS; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Korea.
  • Lee SC; Department of Functional Genomics, University of Science and Technology (UST), Daejeon, 34141, Korea.
  • Hwang GS; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Korea.
  • Lee EW; Department of Functional Genomics, University of Science and Technology (UST), Daejeon, 34141, Korea.
Nat Commun ; 14(1): 5728, 2023 09 15.
Article em En | MEDLINE | ID: mdl-37714840
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ferroptose / Neoplasias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ferroptose / Neoplasias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article