Towards a platform quantitative systems pharmacology (QSP) model for preclinical to clinical translation of antibody drug conjugates (ADCs).

Scheuher, Bruna; Ghusinga, Khem Raj; McGirr, Kimiko; Nowak, Maksymilian; Panday, Sheetal; Apgar, Joshua; Subramanian, Kalyanasundaram; Betts, Alison

Scheuher, Bruna; Ghusinga, Khem Raj; McGirr, Kimiko; Nowak, Maksymilian; Panday, Sheetal; Apgar, Joshua; Subramanian, Kalyanasundaram; Betts, Alison.

Afiliação

Scheuher B; Applied BioMath, 561 Virginia Road, Concord, MA, 01742, USA.
Ghusinga KR; DMPK and Modeling, Takeda, Boston, MA, United States.
McGirr K; Applied BioMath, 561 Virginia Road, Concord, MA, 01742, USA.
Nowak M; Applied BioMath, 561 Virginia Road, Concord, MA, 01742, USA.
Panday S; Applied BioMath, 561 Virginia Road, Concord, MA, 01742, USA.
Apgar J; Applied BioMath, 561 Virginia Road, Concord, MA, 01742, USA.
Subramanian K; Applied BioMath, 561 Virginia Road, Concord, MA, 01742, USA.
Betts A; Applied BioMath, 561 Virginia Road, Concord, MA, 01742, USA.

J Pharmacokinet Pharmacodyn ; 2023 Oct 03.

Article em En | MEDLINE | ID: mdl-37787918

Palavras-chave

Antibody drug conjugate; Enhertu; HER2; Kadcyla; Oncology; Quantitative systems pharmacology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: J Pharmacokinet Pharmacodyn Assunto da revista: FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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