Dormant tumors circumvent tumor-specific adaptive immunity by establishing a Treg-dominated niche via DKK3.

Trotter, Timothy N; Dagotto, Carina E; Serra, Delila; Wang, Tao; Yang, Xiao; Acharya, Chaitanya R; Wei, Junping; Lei, Gangjun; Lyerly, H Kim; Hartman, Zachary C

Trotter, Timothy N; Dagotto, Carina E; Serra, Delila; Wang, Tao; Yang, Xiao; Acharya, Chaitanya R; Wei, Junping; Lei, Gangjun; Lyerly, H Kim; Hartman, Zachary C.

Afiliação

Trotter TN; Department of Surgery, and.
Dagotto CE; Department of Surgery, and.
Serra D; Department of Surgery, and.
Wang T; Department of Surgery, and.
Yang X; Department of Surgery, and.
Acharya CR; Department of Surgery, and.
Wei J; Department of Surgery, and.
Lei G; Department of Surgery, and.
Lyerly HK; Department of Surgery, and.
Hartman ZC; Department of Pathology/Integrative Immunobiology, Duke University, Durham, North Carolina, USA.

JCI Insight ; 8(22)2023 Nov 22.

Article em En | MEDLINE | ID: mdl-37847565

Assuntos

Neoplasias da Mama; Linfócitos T Reguladores; Humanos; Feminino; Linfócitos T Citotóxicos; Neoplasias da Mama/patologia; Terapia de Imunossupressão; Imunidade Adaptativa; Microambiente Tumoral; Proteínas Adaptadoras de Transdução de Sinal/metabolismo

Palavras-chave

Breast cancer; Cancer immunotherapy; Immunology; Oncology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Linfócitos T Reguladores Limite: Female / Humans Idioma: En Revista: JCI Insight Ano de publicação: 2023 Tipo de documento: Article

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