Development and application of a systematic and quantitative weighting framework to evaluate the quality and relevance of relative potency estimates for dioxin-like compounds (DLCs) for human health risk assessment.

Wikoff, Daniele; Ring, Caroline; DeVito, Michael; Walker, Nigel; Birnbaum, Linda; Haws, Laurie

Wikoff, Daniele; Ring, Caroline; DeVito, Michael; Walker, Nigel; Birnbaum, Linda; Haws, Laurie.

Afiliação

Wikoff D; ToxStrategies, Asheville, NC, USA. Electronic address: dwikoff@toxstrategies.com.
Ring C; ToxStrategies, Austin, TX, USA.
DeVito M; Environmental Protection Agency, Center for Computational Toxicology and Exposure, Research Triangle Park, NC, USA.
Walker N; National Institute of Environmental Health Sciences/National Institutes of Health, Research Triangle Park, NC, USA.
Birnbaum L; National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA; Nicholas School of the Environment, Duke University, Durham, NC, USA.
Haws L; ToxStrategies, Austin, TX, USA.

Regul Toxicol Pharmacol ; 145: 105500, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37866700

Assuntos

Dioxinas; Bifenilos Policlorados; Dibenzodioxinas Policloradas; Humanos; Dioxinas/toxicidade; Medição de Risco; Incerteza; Bases de Dados Factuais

Palavras-chave

Bayesian; Dioxins; Integration; PCBs; Quality; REPs; Relative potency; Risk assessment; TEFs

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bifenilos Policlorados / Dioxinas / Dibenzodioxinas Policloradas Limite: Humans Idioma: En Revista: Regul Toxicol Pharmacol Ano de publicação: 2023 Tipo de documento: Article

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