APOL1-G2 accelerates nephrocyte cell death by inhibiting the autophagy pathway.

Zhu, Jun-Yi; Lee, Jin-Gu; Fu, Yulong; van de Leemput, Joyce; Ray, Patricio E; Han, Zhe

Zhu, Jun-Yi; Lee, Jin-Gu; Fu, Yulong; van de Leemput, Joyce; Ray, Patricio E; Han, Zhe.

Afiliação

Zhu JY; Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Lee JG; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Fu Y; Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
van de Leemput J; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Ray PE; Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Han Z; Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

Dis Model Mech ; 16(12)2023 Dec 01.

Article em En | MEDLINE | ID: mdl-37969018

Assuntos

Drosophila melanogaster; Nefropatias; Animais; Camundongos; Humanos; Drosophila melanogaster/metabolismo; Apolipoproteína L1/genética; Apolipoproteína L1/metabolismo; Morte Celular; Camundongos Transgênicos; Autofagia/genética; Mamíferos/metabolismo

Palavras-chave

Drosophila; APOL1; Autophagy; Endocytosis; Nephrocyte; Podocyte

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Drosophila melanogaster / Nefropatias Limite: Animals / Humans Idioma: En Revista: Dis Model Mech Assunto da revista: MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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