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Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer.
Anantharajan, Jothi; Tan, Qian Wen; Fulwood, Justina; Sifang, Wang; Huang, Qiwei; Ng, Hui Qi; Koh, Xiaoying; Xu, Weijun; Cherian, Joseph; Baburajendran, Nithya; Kang, CongBao; Ke, Zhiyuan.
Afiliação
  • Anantharajan J; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore.
  • Tan QW; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore.
  • Fulwood J; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore.
  • Sifang W; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore.
  • Huang Q; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore.
  • Ng HQ; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore.
  • Koh X; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore.
  • Xu W; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore.
  • Cherian J; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore.
  • Baburajendran N; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore. Electronic address: nithya_baburajendran@eddc.sg.
  • Kang C; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore. Electronic address: Kang_congbao@eddc.sg.
  • Ke Z; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, #5-01, 138670, Singapore. Electronic address: ke_zhiyuan@eddc.sg.
Biochem Biophys Res Commun ; 689: 149238, 2023 12 31.
Article em En | MEDLINE | ID: mdl-37979329

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteína / Ubiquitina Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Singapura

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteína / Ubiquitina Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Singapura