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EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma.
Lv, Deguan; Zhong, Cuiqing; Dixit, Deobrat; Yang, Kailin; Wu, Qiulian; Godugu, Bhaskar; Prager, Briana C; Zhao, Guofeng; Wang, Xiuxing; Xie, Qi; Bao, Shideng; He, Chuan; Heiland, Dieter Henrik; Rosenfeld, Michael G; Rich, Jeremy N.
Afiliação
  • Lv D; UPMC Hillman Cancer Center and Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Zhong C; UPMC Hillman Cancer Center and Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Dixit D; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Yang K; Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic, Cleveland, OH 44195, USA.
  • Wu Q; UPMC Hillman Cancer Center and Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Godugu B; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA.
  • Prager BC; Department of Neurosurgery, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Zhao G; Howard Hughes Medical Institute, Department and School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Wang X; School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
  • Xie Q; Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Westlake University, Hangzhou, Zhejiang 310024, China.
  • Bao S; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
  • He C; Department of Chemistry and Institute for Biophysical Dynamics, University of Chicago, Chicago, IL 60637, USA.
  • Heiland DH; Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg, Germany.
  • Rosenfeld MG; Howard Hughes Medical Institute, Department and School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Rich JN; UPMC Hillman Cancer Center and Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA. Electronic address: drjeremyrich@gmail.com.
Mol Cell ; 83(23): 4334-4351.e7, 2023 Dec 07.
Article em En | MEDLINE | ID: mdl-37979586
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glioblastoma / Receptores ErbB / Homólogo AlkB 5 da RNA Desmetilase / Ferroptose Limite: Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glioblastoma / Receptores ErbB / Homólogo AlkB 5 da RNA Desmetilase / Ferroptose Limite: Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos