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CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors.
Wang, Jiawan; Calizo, Ana; Zhang, Lindy; Pino, James C; Lyu, Yang; Pollard, Kai; Zhang, Xiaochun; Larsson, Alex T; Conniff, Eric; Llosa, Nicolas J; Wood, David K; Largaespada, David A; Moody, Susan E; Gosline, Sara J; Hirbe, Angela C; Pratilas, Christine A.
Afiliação
  • Wang J; Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins, Department of Oncology and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Calizo A; Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins, Department of Oncology and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Zhang L; Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins, Department of Oncology and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Pino JC; Pacific Northwest National Laboratory (PNNL), Seattle, WA, USA.
  • Lyu Y; Division of Oncology, Department of Internal Medicine, Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Pollard K; Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins, Department of Oncology and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Zhang X; Division of Oncology, Department of Internal Medicine, Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Larsson AT; Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
  • Conniff E; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA.
  • Llosa NJ; Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins, Department of Oncology and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Wood DK; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA.
  • Largaespada DA; Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
  • Moody SE; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Gosline SJ; Pacific Northwest National Laboratory (PNNL), Seattle, WA, USA.
  • Hirbe AC; Division of Oncology, Department of Internal Medicine, Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Pratilas CA; Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins, Department of Oncology and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Sci Adv ; 9(47): eadg8876, 2023 11 24.
Article em En | MEDLINE | ID: mdl-38000020
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurofibrossarcoma Limite: Humans Idioma: En Revista: Sci Adv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurofibrossarcoma Limite: Humans Idioma: En Revista: Sci Adv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos