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Evaluation of the safety, efficacy, and mechanism of action of obexelimab for the treatment of patients with IgG4-related disease: an open-label, single-arm, single centre, phase 2 pilot trial.
Perugino, Cory A; Wallace, Zachary S; Zack, Debra J; Quinn, Shauna M; Poma, Allen; Fernandes, Ana D; Foster, Paul; DeMattos, Steve; Burington, Bart; Liu, Hang; Allard-Chamard, Hugues; Smith, Nathan; Kai, Xin; Xing, Kelly; Pillai, Shiv; Stone, John H.
Afiliação
  • Perugino CA; Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA, USA.
  • Wallace ZS; Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Zack DJ; Xencor, Pasadena, CA, USA.
  • Quinn SM; Clinical Development, Zenas BioPharma, Waltham, MA, USA.
  • Poma A; Clinical Development, Zenas BioPharma, Waltham, MA, USA.
  • Fernandes AD; Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Foster P; Xencor, Pasadena, CA, USA.
  • DeMattos S; Xencor, Pasadena, CA, USA.
  • Burington B; Xencor, Pasadena, CA, USA.
  • Liu H; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA, USA.
  • Allard-Chamard H; Division of Rheumatology, Faculté de médecine et des sciences de la santé de l'Université de Sherbrooke et Centre de Recherche Clinique Étienne-Le Bel, Sherbrooke, QC, Canada.
  • Smith N; Penn State College of Medicine, Hershey, PA, USA.
  • Kai X; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA, USA.
  • Xing K; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA, USA.
  • Pillai S; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA, USA.
  • Stone JH; Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: jhstone@mgh.harvard.edu.
Lancet Rheumatol ; 5(8): e442-e450, 2023 Aug.
Article em En | MEDLINE | ID: mdl-38251576
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença Relacionada a Imunoglobulina G4 / Antineoplásicos Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Rheumatol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença Relacionada a Imunoglobulina G4 / Antineoplásicos Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Rheumatol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos