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Solid pseudopapillary neoplasms of the pancreas: Multicenter Vasepa study.
Alvarez, Xiomara Duque; Fernando Alcázar, Cándido; Hernando Sanz, Ana; Mora Oliver, Isabel; Granel, Laura; Barreras, José A; Calero, Alicia; Carbonell Morote, Silvia; Domingo, Carlos; Estevan, Rafael; Oliver, Israel; López Andujar, Rafael; Sabater, Luis; Compañ, Antonio; Ramia, José M.
Afiliação
  • Alvarez XD; Departamento de Cirugía, Hospital General Universitario Dr. Balmis, Alicante, Spain. Electronic address: nxiomara060@gmail.com.
  • Fernando Alcázar C; Departamento de Cirugía, Hospital General Universitario Dr. Balmis, Alicante, Spain.
  • Hernando Sanz A; Departamento de Cirugía, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
  • Mora Oliver I; Departamento de Cirugía, Hospital Clínico Universitario de Valencia, Valencia, Spain.
  • Granel L; Departamento de Cirugía, Hospital General Universitario de Castellón, Castellón, Spain.
  • Barreras JA; Departamento de Cirugía, Hospital General Universitario de Elche, Elche, Spain.
  • Calero A; Departamento de Cirugía, Hospital General Universitario de Elche, Elche, Spain.
  • Carbonell Morote S; Departamento de Cirugía, Hospital General Universitario Dr. Balmis, Alicante, Spain.
  • Domingo C; Departamento de Cirugía, Hospital Universitario Doctor Peset, Valencia, Spain.
  • Estevan R; Departamento de Cirugía, Instituto Valenciano de Oncología, Valencia, Spain.
  • Oliver I; Departamento de Cirugía, Hospital General Marina Baja Villajoyosa. Villajoyosa, Spain.
  • López Andujar R; Departamento de Cirugía, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
  • Sabater L; Departamento de Cirugía, Hospital Clínico Universitario de Valencia, Valencia, Spain.
  • Compañ A; Departamento de Cirugía, Hospital General Universitario San Juan, Alicante, Spain; Universidad Miguel Hernández, Campus Sant Joan Alicante, Spain.
  • Ramia JM; Departamento de Cirugía, Hospital General Universitario Dr. Balmis, Alicante, Spain; Universidad Miguel Hernández, Campus Sant Joan Alicante, Spain.
Cir Esp (Engl Ed) ; 102(6): 307-313, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38355041
ABSTRACT

INTRODUCTION:

Solid pseudopapillary tumors (SPT) of the pancreas are rare exocrine neoplasms of the pancreas. Correct preoperative diagnosis is not always feasible. The treatment of choice is surgical excision. These tumors have a good prognosis with a high disease-free survival rate.

OBJECTIVE:

To describe the clinicopathological and radiological characteristics as well as short- and long-term follow-up results of patients who have undergone SPT resection.

METHODS:

Multicenter retrospective observational study in patients with SPT who had undergone surgery from January 2000-January 2022. We have studied preoperative, intraoperative, and postoperative variables as well as the follow-up results (mean 28 months).

RESULTS:

20 patients with histological diagnosis of SPT in the surgical specimen were included. 90% were women; mean age was 33.5 years (13-67); 50% were asymptomatic. CT was the most used diagnostic test (90%). The most frequent location was body-tail (60%). Preoperative biopsy was performed in 13 patients (65%), which was correct in 8 patients. Surgeries performed 7 distal pancreatectomies, 6 pancreaticoduodenectomies, 4 central pancreatectomies, 2 enucleations, and 1 total pancreatectomy. The R0 rate was 95%. Four patients presented major postoperative complications (Clavien-Dindo > II). Mean tumor size was 81 mm. Only one patient received adjuvant chemotherapy. With a mean follow-up of 28 months, 5-year disease-free survival was 95%.

CONCLUSION:

SPT are large, usually located in the body-tail of the pancreas, and more frequent in women. The R0 rate obtained in our series is very high (95%). The oncological results are excellent.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pancreatectomia / Neoplasias Pancreáticas Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cir Esp (Engl Ed) Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pancreatectomia / Neoplasias Pancreáticas Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cir Esp (Engl Ed) Ano de publicação: 2024 Tipo de documento: Article