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3D imaging of aqueous veins and surrounding sclera using a dual-wavelength photoacoustic microscopy.
Ni, Linyu; Zhang, Wei; Kim, Wonsuk; Warchock, Alexus; Bicket, Amanda; Wang, Xueding; Moroi, Sayoko E; Argento, Alan; Xu, Guan.
Afiliação
  • Ni L; Department of Ophthalmology and Visual Sciences, Department of Biomedical Engineering, University of Michigan, 500 S. State St., Ann Arbor, MI 48109, USA.
  • Zhang W; Department of Biomedical Engineering, University of Michigan, 500 S. State St., Ann Arbor, MI 48109, USA.
  • Kim W; Department of Ophthalmology and Visual Sciences, Department of Biomedical Engineering, University of Michigan, 500 S. State St., Ann Arbor, MI 48109, USA.
  • Warchock A; Department of Biomedical Engineering, University of Michigan, 500 S. State St., Ann Arbor, MI 48109, USA.
  • Bicket A; Department of Mechanical Engineering, University of Michigan-Dearborn, 4901 Evergreen Road, Dearborn, MI 48128, USA.
  • Wang X; Department of Ophthalmology and Visual Sciences, Department of Biomedical Engineering, University of Michigan, 500 S. State St., Ann Arbor, MI 48109, USA.
  • Moroi SE; Department of Mechanical Engineering, University of Michigan-Dearborn, 4901 Evergreen Road, Dearborn, MI 48128, USA.
  • Argento A; Department of Ophthalmology and Visual Sciences, Department of Biomedical Engineering, University of Michigan, 500 S. State St., Ann Arbor, MI 48109, USA.
  • Xu G; Department of Biomedical Engineering, University of Michigan, 500 S. State St., Ann Arbor, MI 48109, USA.
Biomed Opt Express ; 14(12): 6291-6300, 2023 Dec 01.
Article em En | MEDLINE | ID: mdl-38420307
ABSTRACT
Understanding aqueous outflow resistance at the level of aqueous veins has been a challenge to the management of glaucoma. This study investigated resolving the anatomies of aqueous veins and the textures of surrounding sclera using photoacoustic microscopy (PAM). A dual wavelength PAM system was established and validated using imaging phantoms, porcine and human globes perfused with an optical contrast agent ex vivo. The system shows lateral resolution of 8.23 µm and 4.70 µm at 1200 nm and 532 nm, respectively, and an axial resolution of 27.6 µm. The system is able to separately distinguish the aqueous veins and the sclera with high contrast in full circumference of the porcine and human globes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biomed Opt Express Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biomed Opt Express Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos