Timing of coronary angiography and use of antiplatelet pretreatment in patients with NSTEACS in Spain.
Rev Esp Cardiol (Engl Ed)
; 77(3): 234-242, 2024 Mar.
Article
em En, Es
| MEDLINE
| ID: mdl-38476000
ABSTRACT
INTRODUCTION AND OBJECTIVES:
The optimal timing of coronary angiography in patients admitted with non-ST-segment elevation acute coronary syndrome (NSTEACS) as well as the need for pretreatment are controversial. The main objective of the IMPACT-TIMING-GO registry was to assess the proportion of patients undergoing an early invasive strategy (0-24hours) without dual antiplatelet therapy (no pretreatment strategy) in Spain.METHODS:
This observational, prospective, and multicenter study included consecutive patients with NSTEACS who underwent coronary angiography that identified a culprit lesion.RESULTS:
Between April and May 2022, we included 1021 patients diagnosed with NSTEACS, with a mean age of 67±12 years (23.6% women). A total of 87% of the patients were deemed at high risk (elevated troponin; electrocardiogram changes; GRACE score>140) but only 37.8% underwent an early invasive strategy, and 30.3% did not receive pretreatment. Overall, 13.6% of the patients underwent an early invasive strategy without pretreatment, while the most frequent strategy was a deferred angiography under antiplatelet pretreatment (46%). During admission, 9 patients (0.9%) died, while major bleeding occurred in 34 (3.3%).CONCLUSIONS:
In Spain, only 13.6% of patients with NSTEACS undergoing coronary angiography received an early invasive strategy without pretreatment. The incidence of cardiovascular and severe bleeding events during admission was low.Palavras-chave
Acute coronary syndrome; Acute myocardial infarction; Bleeding; Coronariografía precoz; Doble antiagregación plaquetaria; Dual antiplatelet therapy; ESC guidelines; Early invasive strategy; Guía ESC; Hemorragia; Infarto agudo de miocardio; NonST-segment elevation acute coronary syndrome; Pretratamiento; Pretreatment; Revascularización; Revascularization; Síndrome coronario agudo; Síndrome coronario agudo sin elevación del segmento ST
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Angiografia Coronária
/
Síndrome Coronariana Aguda
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Europa
Idioma:
En
/
Es
Revista:
Rev Esp Cardiol (Engl Ed)
Ano de publicação:
2024
Tipo de documento:
Article