Adherence to general national dietary guidelines and risk of psoriasis: results from a general population study of 105 332 individuals.
Clin Exp Dermatol
; 49(10): 1131-1139, 2024 Sep 18.
Article
em En
| MEDLINE
| ID: mdl-38545676
ABSTRACT
BACKGROUND:
It is unknown if an unhealthy diet can affect the risk of developing psoriasis.OBJECTIVES:
To test the hypothesis that individuals with an unhealthy diet have an increased risk of prevalent and incident psoriasis.METHODS:
We included 105 332 adults from the Copenhagen General Population Study, who were invited to participate between 2003 and 2015. The response rate was 43%. An unhealthy vs. healthy diet was defined according to adherence to general national dietary guidelines. The participants were grouped into three groups low, intermediate and high adherence to general national dietary guidelines; this was based on information from a food frequency questionnaire. Identification of psoriasis was made using International Classification of Diseases codes.RESULTS:
Of the 105 332 individuals, 580 had a diagnosis of psoriasis at the time of enrolment and 640 received a diagnosis during the median follow-up of 9â years. Risk of prevalent psoriasis increased according to nonadherence to general national dietary guidelines in a stepwise manner with an age- and sex-adjusted odds ratio of 1.70 (95% confidence interval 1.26-2.30) in individuals with low vs. high adherence to dietary guidelines. Results were similar in a multivariable-adjusted model. Prospective analyses adjusted for age and sex showed a weak association between nonadherence to dietary guidelines and risk of incident psoriasis (P for trend 0.04). This association disappeared, when adjusting for multiple confounders (P for trend 0.50).CONCLUSIONS:
Although individuals with psoriasis have an unhealthier diet, diet alone does not appear to independently increase the risk of developing psoriasis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psoríase
Limite:
Adult
/
Aged
/
Female
/
Humans
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Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Clin Exp Dermatol
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Dinamarca