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Is aortic knob width a novel predictor of mortality in hemodialysis patients?
Kaya, B; Mete, B; Balal, M; Seyrek, N; Karayaylali, I.
Afiliação
  • Kaya B; Department of Nephrology, Faculty of Medicine, Çukurova University, Adana, Turkey. bkaya@cu.edu.tr.
Eur Rev Med Pharmacol Sci ; 28(7): 2805-2816, 2024 Apr.
Article em En | MEDLINE | ID: mdl-38639520
ABSTRACT

OBJECTIVE:

Identifying reliable predictors of mortality in end-stage renal disease patients is crucial for patient outcomes. Aortic knob width is a radiographic parameter used to assess cardiovascular diseases and atherosclerosis. This study investigated the association between aortic knob width and mortality in hemodialysis patients. PATIENTS AND

METHODS:

The study included data collected between 2007 and 2022 from 103 patients aged between 18 and 85 who had been undergoing hemodialysis treatment for at least one year. Patients were divided into two groups survivors and deceased. The aortic knob width was measured using a posterior-anterior chest radiograph after midweek hemodialysis. The relationship between aortic knob width and mortality was investigated.

RESULTS:

Deceased patients had significantly larger aortic knob widths compared with survivors. The deceased group's hemodialysis (HD) duration was shorter, median age was older, Kt/V, hemoglobin, and albumin levels were lower, and the frequency of patients with hypertension, diabetes, and aortic wall calcification was higher. Aortic knob width greater than 37.98 mm was identified as a predictor of mortality in hemodialysis patients. Survival rates for aortic knob width <37.98 mm are 98.1% for 1 year and 64.9% for 15 years. For aortic knob width larger than 37.98 mm, survival rates are 88% for three years, 68% for five years, 45.2% for ten years, and 25% for fifteen years. The most important risk factors for increased aortic knob width were age, male sex, aortic calcification, and hypertension.

CONCLUSIONS:

Age, male gender, aortic calcification, and hypertension are the primary risk factors for increased aortic knob width in hemodialysis patients. Aortic knob width greater than 37.98 mm, which can be measured simply and rapidly using posterior-anterior chest radiography, may be a predictor of mortality. Graphical Abstract https//www.europeanreview.org/wp/wp-content/uploads/Graphical-Abstract-10.jpg.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Aterosclerose / Hipertensão / Falência Renal Crônica Limite: Adolescent / Adult / Aged / Aged80 / Humans / Male / Middle aged Idioma: En Revista: Eur Rev Med Pharmacol Sci Assunto da revista: FARMACOLOGIA / TOXICOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Turquia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Aterosclerose / Hipertensão / Falência Renal Crônica Limite: Adolescent / Adult / Aged / Aged80 / Humans / Male / Middle aged Idioma: En Revista: Eur Rev Med Pharmacol Sci Assunto da revista: FARMACOLOGIA / TOXICOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Turquia