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Electron beam response corrections for an ultra-high-dose-rate capable diode dosimeter.
Dai, Tianyuan; Sloop, Austin M; Schönfeld, Andreas; Flatten, Veronika; Kozelka, Jakub; Hildreth, Jeff; Bill, Simon; Sunnerberg, Jacob P; Clark, Megan A; Jarvis, Lesley; Pogue, Brian W; Bruza, Petr; Gladstone, David J; Zhang, Rongxiao.
Afiliação
  • Dai T; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
  • Sloop AM; Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan Shandong, China.
  • Schönfeld A; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
  • Flatten V; Sun Nuclear Corp, Melbourne, Florida, USA.
  • Kozelka J; Sun Nuclear Corp, Melbourne, Florida, USA.
  • Hildreth J; Sun Nuclear Corp, Melbourne, Florida, USA.
  • Bill S; Sun Nuclear Corp, Melbourne, Florida, USA.
  • Sunnerberg JP; Sun Nuclear Corp, Melbourne, Florida, USA.
  • Clark MA; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
  • Jarvis L; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
  • Pogue BW; Department of Medicine, Geisel School of Medicine, Dartmouth College Hanover, Lebanon, New Hampshire, USA.
  • Bruza P; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
  • Gladstone DJ; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
  • Zhang R; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Med Phys ; 51(8): 5738-5745, 2024 Aug.
Article em En | MEDLINE | ID: mdl-38762909
ABSTRACT

BACKGROUND:

Ultra-high-dose-rate (UHDR) electron beams have been commonly utilized in FLASH studies and the translation of FLASH Radiotherapy (RT) to the clinic. The EDGE diode detector has potential use for UHDR dosimetry albeit with a beam energy dependency observed.

PURPOSE:

The purpose is to present the electron beam response for an EDGE detector in dependence on beam energy, to characterize the EDGE detector's response under UHDR conditions, and to validate correction factors derived from the first detailed Monte Carlo model of the EDGE diode against measurements, particularly under UHDR conditions.

METHODS:

Percentage depth doses (PDDs) for the UHDR Mobetron were measured with both EDGE detectors and films. A detailed Monte Carlo (MC) model of the EDGE detector has been configured according to the blueprint provided by the manufacturer under an NDA agreement. Water/silicon dose ratios of EDGE detector for a series of mono-energetic electron beams have been calculated. The dependence of the water/silicon dose ratio on depth for a FLASH relevant electron beam was also studied. An analytical approach for the correction of PDD measured with EDGE detectors was established.

RESULTS:

Water/silicon dose ratio decreased with decreasing electron beam energy. For the Mobetron 9 MeV UHDR electron beam, the ratio decreased from 1.09 to 1.03 in the build-up region, maintained in range of 0.98-1.02 at the fall-off region and raised to a plateau in value of 1.08 at the tail. By applying the corrections, good agreement between the PDDs measured by the EDGE detector and those measured with film was achieved.

CONCLUSIONS:

Electron beam response of an UHDR capable EDGE detector was derived from first principles utilizing a sophisticated MC model. An analytical approach was validated for the PDDs of UHDR electron beams. The results demonstrated the capability of EDGE detector in measuring PDDs of UHDR electron beams.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Método de Monte Carlo / Elétrons Idioma: En Revista: Med Phys Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Método de Monte Carlo / Elétrons Idioma: En Revista: Med Phys Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos