Your browser doesn't support javascript.
loading
Association between tumor-infiltrating lymphocytes and survival in patients with metastatic breast cancer receiving first-line chemotherapy: analysis of CALGB 40502.
Stover, Daniel G; Salgado, Roberto; Savenkov, Oleksander; Ballman, Karla; Mayer, Erica L; Magbanua, Mark Jesus M; Loi, Sherene; Vater, Mark; Glover, Kristyn; Watson, Mark; Wen, Yujia; Symmans, W Fraser; Perou, Charles; Carey, Lisa A; Partridge, Ann H; Rugo, Hope S.
Afiliação
  • Stover DG; Division of Medical Oncology, Department of Medicine, The Ohio State University College of Medicine, Columbus, OH, USA. daniel.stover@osumc.edu.
  • Salgado R; Pelotonia Institute for ImmunoOncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA. daniel.stover@osumc.edu.
  • Savenkov O; GZA-ZNA Hospitals, Antwerp, Belgium.
  • Ballman K; Division of Research, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Mayer EL; Alliance Statistics and Data Management Center, Weill-Cornell Medical College, New York, NY, USA.
  • Magbanua MJM; Alliance Statistics and Data Management Center, Weill-Cornell Medical College, New York, NY, USA.
  • Loi S; Dana-Farber/Partners CancerCare, Boston, MA, USA.
  • Vater M; University of California, San Francisco, San Francisco, CA, USA.
  • Glover K; Division of Research, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Watson M; Division of Medical Oncology, Department of Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Wen Y; Division of Medical Oncology, Department of Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Symmans WF; Washington University School of Medicine, St. Louis, MO, USA.
  • Perou C; Alliance Protocol Operations Office, University of Chicago, Chicago, IL, USA.
  • Carey LA; University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
  • Partridge AH; University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.
  • Rugo HS; University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.
NPJ Breast Cancer ; 10(1): 75, 2024 Aug 21.
Article em En | MEDLINE | ID: mdl-39169033
ABSTRACT
Association of stromal tumor-infiltrating lymphocytes (sTILs) with survival outcomes among patients with metastatic breast cancer (MBC) remains unclear. The primary objective was to evaluate the association of sTILs with progression-free survival in randomized phase III trial CALGB 40502. sTILs were associated with progression-free and overall survival in chemotherapy-treated MBC when controlling for treatment arm; however, this effect did not remain significant after additional adjustment for hormone receptor status. CALGB is now part of the Alliance for Clinical Trials in Oncology. Trial Registration ClinicalTrials.gov NCT00785291.
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: NPJ Breast Cancer Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: NPJ Breast Cancer Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos