The effect of clinical decision support systems on clinical outcomes in acute kidney injury: a systematic review and meta-analysis of randomized controlled trials.
Ren Fail
; 46(2): 2400552, 2024 Dec.
Article
em En
| MEDLINE
| ID: mdl-39252153
ABSTRACT
OBJECTIVES:
To determine whether clinical decision support systems (CDSS) for acute kidney injury (AKI) would enhance patient outcomes in terms of mortality, dialysis, and acute kidney damage progression.METHODS:
The systematic review and meta-analysis included the relevant randomized controlled trials (RCTs) retrieved from PubMed, EMBASE, Web of Science, Cochrane, and SCOPUS databases until 21st January 2024. The meta-analysis was done using (RevMan 5.4.1). PROSPERO ID CRD42024517399.RESULTS:
Our meta-analysis included ten RCTs with 18,355 patients. There was no significant difference between CDSS and usual care in all-cause mortality (RR 1.00 with 95% CI [0.93, 1.07], p = 0.91) and renal replacement therapy (RR 1.11 with 95% CI [0.99, 1.24], p = 0.07). However, CDSS was significantly associated with a decreased incidence of hyperkalemia (RR 0.27 with 95% CI [0.10, 0.73], p = 0.01) and increased eGFR change (MD 1.97 with 95% CI [0.47, 3.48], p = 0.01).CONCLUSIONS:
CDSS were not associated with clinical benefit in patients with AKI, with no effect on all-cause mortality or the need for renal replacement therapy. However, CDSS reduced the incidence of hyperkalemia and improved eGFR change in AKI patients.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ensaios Clínicos Controlados Aleatórios como Assunto
/
Sistemas de Apoio a Decisões Clínicas
/
Injúria Renal Aguda
Limite:
Humans
Idioma:
En
Revista:
Ren Fail
Assunto da revista:
NEFROLOGIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Jordânia