Topical indomethacin therapy before argon laser trabeculoplasty.
Am J Ophthalmol
; 99(5): 571-5, 1985 May 15.
Article
em En
| MEDLINE
| ID: mdl-4003494
ABSTRACT
Fifty treatment sessions for 43 eyes (35 patients) receiving argon laser trabeculoplasty to one-half the angle were randomly assigned in a double-masked fashion to pretreatment with either topical indomethacin 1% or placebo. In 25 treatments intraocular pressure increased 3 mm Hg or more within four hours. Topical indomethacin pretreatment had no effect on the incidence, magnitude, or time course of this acute increase. It also did not alter the long-term effectiveness of the laser treatment (-3.8 mm Hg in the indomethacin-treated group vs -4.3 mm Hg in the placebo-treated group). The overall incidence of new peripheral anterior synechiae found on gonioscopy at one month was 32% (16 of 50 treatments). Synechiae formation was much higher in blacks (ten of 11 eyes or 91%) than in whites (five of 38 eyes or 13%). Although there was an association between acute anterior chamber inflammation after laser treatment and ultimate synechia formation (P less than .05), indomethacin pretreatment did not alter its occurrence.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
/
Malha Trabecular
/
Indometacina
/
Terapia a Laser
Tipo de estudo:
Clinical_trials
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Am J Ophthalmol
Ano de publicação:
1985
Tipo de documento:
Article