Colcemid sensitivity of fission yeast and the isolation of colcemid-resistant mutants.
Science
; 168(3930): 485-7, 1970 Apr 24.
Article
em En
| MEDLINE
| ID: mdl-5436084
ABSTRACT
Cell division of the fission yeast, Schizosaccharomyces pombe, is reversibly inhibited by the antimitotic agent Colcemid (N-deacetyl-N-methylcolchicine) in nutrient medium. Cell growth continiues until all cells become nonseparating cell doublets in a V configuration. Mutants have been isolated capable of uninhibited growth in the presence of concentrations of Colcemid mycostatic for the parent strain.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Saccharomyces
/
Resistência Microbiana a Medicamentos
/
Divisão Celular
/
Colchicina
/
Mutação
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
Science
Ano de publicação:
1970
Tipo de documento:
Article