Axonal transport: each major rate component reflects the movement of distinct macromolecular complexes.
Science
; 214(4517): 179-81, 1981 Oct 09.
Article
em En
| MEDLINE
| ID: mdl-6169148
ABSTRACT
The proteins of the three major rate components of axonal transport in guinea pig retinal ganglion cells were analyzed by one- and two-dimensional gel electrophoresis. Each rate component consisted of a different set of proteins that remained associated with each other during transport. This suggests that each rate component represents a distinct macromolecular complex and that these complexes may be definable organelles such as microtubules, microfilaments, and smooth endoplasmic reticulum. Thus, the transport of radiolabeled proteins in the axon reflects the movement of complete subcellular rather than the movement of individual proteins.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Axônios
/
Transporte Axonal
/
Proteínas do Tecido Nervoso
Limite:
Animals
Idioma:
En
Revista:
Science
Ano de publicação:
1981
Tipo de documento:
Article