Chlorozotocin treatment of advanced gastrointestinal cancer.
Med Pediatr Oncol
; 11(5): 365-6, 1983.
Article
em En
| MEDLINE
| ID: mdl-6226856
ABSTRACT
From April 1981 to December 1981, 34 consecutive patients with advanced gastrointestinal cancer were treated with chlorozotocin at the dosage of 40 mg/m2 daily for 5 consecutive days (30 mg/m2 in patients pretreated with chemotherapy) every 6 weeks. In the 30 patients evaluable for response, a 3.3% objective response rate was encountered. Toxicity was not significant and consisted mainly in reversible myelosuppression. Median survival was 3 months. At the dosage and schedule used, chlorozotocin does not seem to be an effective agent in the treatment of advanced gastrointestinal cancer.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estreptozocina
/
Neoplasias Gastrointestinais
/
Antineoplásicos
Tipo de estudo:
Diagnostic_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Med Pediatr Oncol
Ano de publicação:
1983
Tipo de documento:
Article