Decreased concentration of myocardial alpha-adrenoceptors with increasing age in foetal lambs.
Br J Pharmacol
; 70(4): 515-7, 1980 Dec.
Article
em En
| MEDLINE
| ID: mdl-6258677
ABSTRACT
Using [3H]-dihydroergocryptine, we identified myocardial alpha-adrenoceptor binding sites in foetal lambs and demonstrated that the concentration of receptors decreased with increasing foetal age. The presence of the receptor in the foetus correlated with the presence of myocardial alpha-adrenergic responsiveness. However, we found neither the alpha-receptor binding site nor responsiveness to alpha-adrenoceptor stimulation in the myocardium of adult sheep.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Receptores Adrenérgicos
/
Receptores Adrenérgicos alfa
/
Coração Fetal
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Br J Pharmacol
Ano de publicação:
1980
Tipo de documento:
Article